69241-43-6

Basic information

• Product Name: 2-(3,4-Dimethoxybenzoyl)furan
• Synonyms: 2-(3,4-Dimethoxybenzoyl)furan
• CAS NO: 69241-43-6
• Molecular Weight: 232.236
• Mol File: 69241-43-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(3,4-Dimethoxybenzoyl)furan(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-Dimethoxybenzoyl)furan(69241-43-6)
• EPA Substance Registry System: 2-(3,4-Dimethoxybenzoyl)furan(69241-43-6)

Safety Data

• Hazardous Substances Data: 69241-43-6(Hazardous Substances Data)

Upstream product

• 110-00-9 furan 
• 2024-83-1 veratronitrile 
• 88-14-2 2-furanoic acid 
• 93-07-2 Veratric acid 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 527-69-5 2-furancarbonyl chloride 
• 91-16-7 1,2-dimethoxybenzene 
• 4131-03-7 bis(3,4-dimethoxyphenyl)methanone 

Downstream Products

• 63688-36-8 2-(3,4-dimethoxy-phenyl)-pyridin-3-ol 
• 1310849-12-7 (3,4-dihydroxyphenyl)(furan-2-yl)methanone 
• 26096-00-4 KED-2-271 
• 69241-46-9 cis-2-(3,4-dimethoxyphenyl)-1-methyl-3-piperidinol 
• 34541-50-9 2-(3,4-dihydroxy-phenyl)-pyridin-3-ol 
• 553665-89-7 (E)-(3,4-dimethoxyphenyl)(furan-2-yl)methanone O-benzyloxime 
• 553665-87-5 (E)-(3,4-dimethoxyphenyl)(furan-2-yl)methanone oxime 

Relevant articles and documents

Synthesis and biological activities of new halophenols

A series of new halophenols were synthesized, and their structures were established on the basis of 1H, 13C NMR and mass spectral data. All of the prepared compounds were screened for their in vitro protein tyrosine kinase (PTK) and vascular smooth muscle cell (VSMC) proliferation inhibitory activity. Twelve halophenols showed significant PTK inhibitory activity, most of them exhibited stronger activities than that of genistein, a positive reference compound. Several halophenols also displayed moderate VSMC proliferation inhibitory activity, compound 8c showed higher activity than that of tetrandrine, a positive reference compound. The preliminary structure-activity relationships of these compounds were investigated and discussed. The results provided a foundation for the action mechanism study and further structure optimization of the halophenols.

Synthesis and in vitro protein tyrosine kinase inhibitory activity of furan-2-yl(phenyl)methanone derivatives

A series of novel furan-2-yl(phenyl)methanone derivatives were synthesized, and their structures were established on the basis of 1H-NMR, 13C-NMR and mass spectral data. All the prepared compounds were screened for their in vitro protein tyrosine kinase inhibitory activity and several new derivatives exhibited promising activity, which, in some cases, was identical to, or even better than that of genistein, a positive reference compound. The preliminary structure-activity relationships of these compounds were investigated and are discussed.

Diuretic [2]benzopyrano[4,3-b]pyridines and process therefor

[2]Benzopyrano[4,3-b]pyridine derivatives characterized by having a 2,3,4,4a,6,10b-hexahydro-1H-[2]benzopyrano[4,3-b]pyridine nucleus bearing substituents at positions 1,6,8 and 9 are disclosed. The derivatives are useful diuretic agents. Methods for their preparation and use also are disclosed.