6928-77-4Relevant articles and documents
Symmetric diarylsulfoxides as asymmetric sulfinylating reagents for dialkylmagnesium compounds
Ruppenthal, Simon,Brückner, Reinhard
, p. 897 - 910 (2015/01/30)
At -78 °C, primary dialkylmagnesium compounds reacted with diarylsulfoxides when 1.5 equiv of the dilithium salt of (S)-BINOL was added as a promotor. Alkyl aryl sulfoxides resulted in up to quantitative yield and with up to 97% ee. This demonstrates the feasibility of asymmetric sulfinylations by achiral sulfinylating agents (from the perspective of Alkyl2Mg) as well as the feasibility of asymmetric sulfoxide-magnesium exchanges (from the perspective of Ar2SO).