693245-09-9Relevant academic research and scientific papers
The first general method for α-trifluoromethylation of carboxylic acids using BrF3
Hagooly, Aviv,Rozen, Shlomo
, p. 594 - 595 (2004)
2-Carbomethoxy-1,1-bis(methylsulfide)-1-alkenes, easily made from carboxylic acids, CS2 and MeI, were treated with BrF3 producing eventually the desired α-trifluoromethyl carboxylate derivatives - RCH(CF3)COOR′ - in good yields.
General method for the preparation of β,β-difluoroacrylates using BrF3
Hagooly, Aviv,Rozen, Shlomo
, p. 8786 - 8788 (2007/10/03)
Various esters were reacted with base, carbon disulfide, and methyl iodide, producing 2-carboalkoxy-1,1-bis(methyl sulfide)-1-alkenes (2). The reaction of 2 with BrF3, followed by oxidation with HOF-CH3CN gave the bromodifluorosulfon
