693244-92-7

Upstream product

• 75-15-0 carbon disulfide 
• 15972-01-7 4-cyclohexylbutyric acid methyl ester 
• 74-88-4 methyl iodide 

Downstream Products

• 693245-09-9 2-bromo-4-cyclohexyl-2-(difluoro-methanesulfonyl-methyl)-butyric acid methyl ester 

Relevant academic research and scientific papers

General method for the preparation of β,β-difluoroacrylates using BrF3

Various esters were reacted with base, carbon disulfide, and methyl iodide, producing 2-carboalkoxy-1,1-bis(methyl sulfide)-1-alkenes (2). The reaction of 2 with BrF3, followed by oxidation with HOF-CH3CN gave the bromodifluorosulfon

The first general method for α-trifluoromethylation of carboxylic acids using BrF3

2-Carbomethoxy-1,1-bis(methylsulfide)-1-alkenes, easily made from carboxylic acids, CS2 and MeI, were treated with BrF3 producing eventually the desired α-trifluoromethyl carboxylate derivatives - RCH(CF3)COOR′ - in good yields.