693259-91-5

Basic information

• Product Name: 7-(4-nitro-phenoxycarbonyloxy)-10-benzyloxy-glinkgolide C
• Synonyms: 7-(4-nitro-phenoxycarbonyloxy)-10-benzyloxy-glinkgolide C
• CAS NO: 693259-91-5
• Molecular Weight: 695.634
• Mol File: 693259-91-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-(4-nitro-phenoxycarbonyloxy)-10-benzyloxy-glinkgolide C(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(4-nitro-phenoxycarbonyloxy)-10-benzyloxy-glinkgolide C(693259-91-5)
• EPA Substance Registry System: 7-(4-nitro-phenoxycarbonyloxy)-10-benzyloxy-glinkgolide C(693259-91-5)

Safety Data

• Hazardous Substances Data: 693259-91-5(Hazardous Substances Data)

Upstream product

• 7693-46-1 4-Nitrophenyl chloroformate 
• 502421-88-7 10-benzyloxy-ginkgolide C 

Relevant articles and documents

SYNTHESIS OF DERIVATIVES OF GINKGOLIDE C

The subject invention provides ginkgolide C derivatives compounds having the structure: wherein R is H or -A-Ar, where A is an alkyl group; and Ar is an aryl group, which may contain heteroatoms and may be unsubstituted or substituted by one to five substituents each selected from the group consisting of hydrogen, alkoxy, -CH2CO2R, and - CH2CONRR; where R is an alkyl group; and R and R are each, independently, hydrogen or a branched or unbranched alkyl group; wherein R is H or -COR, where R is alkyl, aryl or amino; wherein R is present or absent, and when present is H, COR or -CO-Z-R; where R is alkyl, aryl or amino; andZ is oxygen; wherein R is present or absent, and when present is -COR; where R is alkyl or aryl; wherein only one of R or R is present in the compound; wherein only two of R, R, R and R are H; and wherein each of a and b designates a single covalent bond which is present or absent, where bond a is present when R is absent and bond b is present when R is absent; or an optically pure enantiomer of the compound. Additionally, the subject invention provides methods of inhibiting the activity of a glycine receptor using these compounds.