69333-42-2Relevant academic research and scientific papers
Effect of the tether length upon Truce-Smiles rearrangement reactions
Fuss, David,Wu, Yu Qi,Grossi, Michael R.,Hollett, Joshua W.,Wood, Tabitha E.
, (2017/10/06)
This report examines the effect of substrate design upon the Truce-Smiles rearrangement, an intramolecular nucleophilic aromatic substitution reaction. The length of the molecular spacer that tethers the carbanion nucleophile to the substituted benzene ri
Efficient and rapid synthesis of phenolic analogs of 4-phenylbutanoic acid using microwave-assisted Michael addition as a key reaction
Iida, Hirokazu,Akatsu, Yusuke,Mizukami, Kazushi,Natori, Sho,Matsukawa, Minako,Takahashi, Kie
supporting information, p. 581 - 585 (2016/07/06)
ABSTRACT: The addition of phenols to acrylonitrile in the presence of aqueous benzyltrimethylammonium hydroxide or tetramethylammonium hydroxide under microwave irradiation yielded the corresponding Michael adducts. The obtained adducts were easily transformed to phenolic analogs of 4-phenylbutanoic acids via the hydrolysis of nitrile groups.
