69337-36-6Relevant academic research and scientific papers
Reaction of 3-alkyl(aryl)-5-chloromethylisoxazoles with nucleophilic reagents
Gadzhily,Potkin,Aliev,Gadzhieva,Petkevich,Dikusar
experimental part, p. 1531 - 1534 (2012/03/09)
Previously unknown 3-alkyl(aryl)isoxazoles containing various functional groups in the 5-position were synthesized by reactions of 3-alkyl(aryl)-5- chloromethylisoxazoles with nucleophiles (2-aminoethanol, methylamine, sodium acetate, and sodium methoxide). Pleiades Publishing, Ltd., 2011.
Silver-catalyzed synthesis of disubstituted isoxazoles by cyclization of alkynyl oxime ethers
Ueda, Masafumi,Ikeda, Yuki,Sato, Aoi,Ito, Yuta,Kakiuchi, Maiko,Shono, Hiroko,Miyoshi, Tetsuya,Naito, Takeaki,Miyata, Okiko
, p. 4612 - 4615 (2011/07/08)
A facile and practical synthesis of 3,5-disubstituted isoxazoles via a silver-catalyzed cyclization and subsequent protonation of alkynyl oxime ethers has been developed. The methodology was successfully applied to the synthesis of a biologically active i
