69360-39-0

Upstream product

• 350-46-9 4-Fluoronitrobenzene 
• 36265-31-3 1-(4-methylsulfanylphenoxy)-4-nitrobenzene 
• 1073-72-9 4-hydroxythioanisole 

Downstream Products

• 73441-59-5 4-(4-methylthiophenoxy)-N-propanoylaniline 
• 69360-41-4 4-[4-(Methylthio)-phenoxy]-phenylhydrazonomalonyldimethan 
• 73441-74-4 4-(4-propanamidophenoxy)phenyl methyl sulphone 
• 36265-31-3 1-(4-methylsulfanylphenoxy)-4-nitrobenzene 
• 1244974-85-3 C₄₂H₂₉F₆N₃O₈S 

Relevant academic research and scientific papers

A focused library of protein tyrosine phosphatase inhibitors

Protein tyrosine phosphatases such as PTP1B and YopH are potential targets for the development of therapeutic agents against a variety of pathological conditions including diabetes, obesity, and infection by the bacterium Yersinia pestis. A focused library of bidentate α-ketoacid-based inhibitors has been screened against several tyrosine phosphatases. Compound 2a has IC 50 values of 43 and 220 nM against YopH and PTP1B, respectively, and shows a 30-fold selectivity for PTP1B over the closely related phosphatase TCPTP.