69361-51-9Relevant academic research and scientific papers
Niobium Pentachloride Mediated (Hetero)aromatic Aldehyde Friedel-Crafts Hydroxyalkylation with Arenes: An Efficient Strategy to Synthesize Triarylmethanes
Baviera, Giovanni S.,Donate, Paulo M.,Matias, Alexandre A.,Previdi, Daniel,Rodrigues, Shirley M. M.
, p. 4498 - 4506 (2019/11/21)
Niobium pentachloride is an efficient and useful Lewis acid to conduct Friedel-Crafts hydroxyalkylation between arenes and (hetero)aromatic aldehydes, to generate triarylmethanes. This practical methodology offers several advantages, such as short reaction time, mild experimental conditions, and excellent yields.
Microwave-assisted nafion-H catalyzed friedel-crafts type reaction of aromatic aldehydes with arenes: Synthesis of triarylmethanes
Prakash, Surya G. K.,Fogassy, Gabriella,Olah, George A.
experimental part, p. 155 - 159 (2011/01/04)
A new solid acid Nafion-H, a perfluorinated sulfonic acid resin, catalyzed microwave-assisted synthesis of triarylmethanes is described. Various benzaldehydes react readily with arenes to provide the corresponding triarylmethanes in good to excellent yields. The reactions were carried out under solvent free conditions under microwave irradiation in a pressure vessel. The solvent free microwave irradiation methods appears to be an environmentally friendly synthetic protocol providing products in significantly shorter reaction times over traditional heating methods carried out in a pressure tube.
Palladium-catalyzed coupling reaction of 4-alkylnitrobenzenes with aryl bromides at their benzylic position
Inoh, Jun-Ichi,Satoh, Tetsuya,Pivsa-Art, Sommai,Miura, Masahiro,Nomura, Masakatsu
, p. 4673 - 4676 (2007/10/03)
4-Alkylnitrobenzenes effectively undergo coupling with aryl bromides at their benzylic position in the presence of a palladium catalyst and a base to give the corresponding mono- and/or di-arylated products in good yields.
