69366-46-7

Basic information

• Product Name: 3-hydroxy-2-methyl-5-phenyl-pent-4-enoic acid
• CAS NO: 69366-46-7
• Molecular Weight: 206.241
• Mol File: 69366-46-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-2-methyl-5-phenyl-pent-4-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-2-methyl-5-phenyl-pent-4-enoic acid(69366-46-7)
• EPA Substance Registry System: 3-hydroxy-2-methyl-5-phenyl-pent-4-enoic acid(69366-46-7)

Safety Data

• Hazardous Substances Data: 69366-46-7(Hazardous Substances Data)

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 66730-60-7 C₃H₄O₂^(2-)*2Li⁽¹⁺⁾ 
• 104-55-2 3-phenyl-propenal 
• 535-11-5 Ethyl 2-bromopropionate 

Downstream Products

• 3909-96-4 (1E,3E)-1-phenyl-1,3-pentadiene 
• 1608-27-1 (Z)-1-phenyl-4-methyl-1,3-butadiene 
• 40136-19-4 2-methyl-5-phenyl-penta-2,4-dienoic acid 

Relevant articles and documents

Additions of Carboxylic Acid Dianions to α,β-Unsaturated Carbonyl Compounds - Control of the 1,2-/1,4-Regioselectivity by Steric Substituent Effects

Dilithium carboxylic acid dianions 1 attack α,β-unsaturated aldehydes (2) 1,2-regiospecifically with formation of the unsaturated β-hydroxy carboxylic acids 3/4.Additionally, the addition of the phenylacetate dianion 1a can be conducted to the threo-isomer with high selectivity by reversible reaction. - α,β-Enones (8) add 1 irreversibly in 1,2- and 1,4-position.Depending on the substitution pattern, the whole range from pure 1,2- to pure 1,4-adduct is covered.The influence of the 1-counterion M and of the solvent is significant; the 1,4-portion increases with the complexing effect of M and with the Lewis-basicity of the solvent.