69366-51-4

Upstream product

• 538-44-3 (E)-benzylidenepinacolone 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 69366-39-8 dilithiated acetic acid 
• 100-42-5 styrene 
• 904319-03-5 3,3-dimethyl-1-buten-2-yl O,O-diphenyl phosphate 
• 75-97-8 3,3-dimethyl-butan-2-one 

Downstream Products

• 116780-18-8 1,c-4-di(tert-butyl)-r-3-phenyl-t-4-<(E)-styryl>-1-cyclohexene 
• 116669-48-8 1,t-4-di(tert-butyl)-r-3-phenyl-c-4-<(E)-styryl>-1-cyclohexene 

Relevant academic research and scientific papers

Heck coupling with nonactivated alkenyl tosylates and phosphates: Examples of effective 1,2-migrations of the alkenyl palladium(II) intermediates

(Chemical Equation Presented) What the Heck! A catalytic system composed of a Pd complex with a basic, hindered alkyl phosphine ligand is capable of promoting Heck coupling of nonactivated vinyl tosylates and phosphates with electron-deficient olefins. An unexpected 1,2-migration of the alkenyl Pd II intermediates (see Scheme) leads to the isomerized Heck coupling product.

Studies on the heck reaction with alkenyl phosphates: Can the 1,2-migration be controlled? Scope and limitations

A catalyst system was identified which promotes the Heck coupling of nonactivated vinyl phosphates with electron deficient alkenes providing a new entry to diene products from simple and readily accessible starting materials. In contrast to our earlier wo

Synthesis of Isomerically Pure (E)- and (Z)-1,3-Disubstituted 1,3-Dienes

The (E)-dienes 1a - p were prepared in >98percent purity by dehydrative decarboxylation of the corresponding 4,5-unsaturated 3-hydroxycarboxylic acids 3 with dimethylformamide dimethylacetal (11).The (Z)-isomers 6a - m were obtained by stereouncontrolled