6937-38-8Relevant articles and documents
Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies
Chigurupati, Sridevi,Selvaraj, Manikandan,Mani, Vasudevan,Selvarajan, Kesavanarayanan Krishnan,Mohammad, Jahidul Islam,Kaveti, Balaji,Bera, Hriday,Palanimuthu, Vasanth Raj,Teh, Lay Kek,Salleh, Mohd Zaki
, p. 9 - 17 (2016)
The synthesis of novel indolopyrazoline derivatives (P1-P4 and Q1-Q4) has been characterized and evaluated as potential anti-Alzheimer agents through in vitro Acetylcholinesterase (AChE) inhibition and radical scavenging activity (antioxidant) studies. Sp
ALLOSTERIC PROTEIN KINASE MODULATORS
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Page/Page column 54, (2012/03/10)
The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.
ALLOSTERIC PROTEIN KINASE MODULATORS
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Page/Page column 112, (2010/04/30)
The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.