69371-19-3

Upstream product

• 541-59-3 maleiimide 
• 108-88-3 toluene 
• 91143-76-9 2-Methylphenyl-succinic acid 

Downstream Products

• 1155401-71-0 N-[(4-phenylpiperazin-1-yl)-methyl]-3-(2-methylphenyl)-pyrrolidine-2,5-dione 
• 1155401-74-3 N-[{4-(2-methoxyphenyl)-piperazin-1-yl}-methyl]-3-(2-methylphenyl)-pyrrolidine-2,5-dione hydrochloride 
• 1155401-72-1 [{4-(2-fluorophenyl)-piperazin-1-yl}-methyl]-3-(2-methylphenyl)-pyrrolidine-2,5-dione 
• 1155401-76-5 N-[{4-(3-trifluoromethylphenyl)-piperazin-1-yl}-methyl]-3-(2-methylphenyl)-pyrrolidine-2,5-dione hydrochloride 
• 1155401-75-4 N-[{4-(3-chlorophenyl)-piperazin-1-yl}-methyl]-3-(2-methylphenyl)-pyrrolidine-2,5-dione 

Relevant academic research and scientific papers

Synthesis and anticonvulsant activity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 3-phenyl-pyrrolidine-2,5-dione

In the present study, on the development of new anticonvulsants, the series of N-[(4-arylpiperazin-1-yl)-alkyl]-3-(2-methylphenyl)- (8a-e, 10a-h) and 3-(2-trifluoromethyl-phenyl)-pyrrolidine-2,5-diones (9a-e, 11a-i) were synthesized and tested for anticon

Superacidic activation of maleimide and phthalimide and their reactions with cyclohexane and arenes

When activated in the CF3SO3H/SbF5 acid system maleimide (1) and phthalimide (2) undergo selective ionic hydrogenation with cyclohexane to give 1,5-dihydropyrrol-2-one (3) and phthalimidine (11), respectively. When treated