69371-38-6Relevant academic research and scientific papers
Synthesis of phospholipids bearing a conjugated oxo-polyunsaturated fatty acid residue
Zhu, Changjin,Ohashi, Takaaki,Morimoto, Tatsuya,Onyango, Arnold N.,Takao, Kaneko,Shimizu, Sakayu,Nakajima, Shuhei,Baba, Naomichi
, p. 500 - 501 (1999)
2-(15'-Oxo-5',8',11',13'-eicosatetraenoyl)-1-stearoyl- sn- glycerol(3)phosphocholine (APC-CO) 1 and 2 and 2-(13'-oxo-9',11'- octadecadienoyl)-1-stearoyl-sn-glycero(3)phosphocholine (LPC-CO) 3 are synthesized and an analytical system established for the determination of geometrical isomers at the 13' position of APC-CO.
Physcomitrella patens has lipoxygenases for both eicosanoid and octadecanoid pathways
Anterola, Aldwin,G?bel, Cornelia,Hornung, Ellen,Sellhorn, George,Feussner, Ivo,Grimes, Howard
experimental part, p. 40 - 52 (2009/07/11)
Mosses have substantial amounts of long chain C20 polyunsaturated fatty acids, such as arachidonic and eicosapentaenoic acid, in addition to the shorter chain C18 α-linolenic and linoleic acids, which are typical substrates of lipoxygenases in flowering p
Iron-mediated generation of the neurotoxin 6-hydroxydopamine quinone by reaction of fatty acid hydroperoxides with dopamine: A possible contributory mechanism for neuronal degeneration in parkinson's disease
Pezzella, Alessandro,D'Ischia, Marco,Napolitano, Alessandra,Misuraca, Giovanna,Prota, Giuseppe
, p. 2211 - 2216 (2007/10/03)
Exposure of dopamine to an excess of linoleic acid 13-hydroperoxide (13- hydroperoxyoetadecadienoic acid) in the presence of ferrous ions in Tris buffer, pH 7.4, resulted in a relatively fast, oxygen-independent reaction exhibiting first-order kinetics wi
Unified Mechanism for Polyunsaturated Fatty Acid Autooxidation. Competition of Peroxy Radical Hydrogen Atom Abstraction, β-Scission, and Cyclization
Porter, Ned A.,Lehman, Laura S.,Weber, Bruce A.,Smith, Karl J.
, p. 6447 - 6455 (2007/10/02)
The autooxidation of linoleic (18:2) and arachidonic (20:4) acids with several cosubstrates was investigated.Cumene, tetralin, 1,4-cyclohexadiene, and 9,10-dihydroanthracene in benzene were used as cosubstrates for the oxidation of linoleic acid.The distribution of products, trans,cis diene hydroperoxides and trans,trans diene hydroperoxides, was dependent on the ability of cosubstrates to donate hydrogen atoms to linoleate peroxy radicals.Arachidonic acid was oxidized in mixtures of benzene/1,4-cyclohexadiene with linoleic acid internal standard.Product distribution of six hydroperoxyeicosatetraenoic acids (HPETE) derived from arachidonic acid was established at different concentrations of 1,4-cyclohexadiene in the solvent mixture.A kinetic expression is derived that is useful in describing polyunsaturated fatty acid oxidation product mixtures.By the use of this kinetic derivation, the rate of cyclization of peroxy free radicals derived from arachidonic acid was determined.
