693790-87-3Relevant academic research and scientific papers
Preparation method and application of 4 -position substituted chiral spiro amine phosphine ligand on pyridine ring (by machine translation)
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Paragraph 0074-0078; 0080, (2019/07/16)
The invention relates to a preparation method and application. of a 4 -position substituted chiral spiro amine phosphine ligand on a pyridine ring. 4 -position substituted chiral spiro amine phosphine ligand in the pyridine 1 ring is a compound, or a race
Enantioselective Hydrogenation of Racemic α-Arylamino Lactones to Chiral Amino Diols with Site-Specifically Modified Chiral Spiro Iridium Catalysts
Gu, Xue-Song,Yu, Na,Yang, Xiao-Hui,Zhu, An-Te,Xie, Jian-Hua,Zhou, Qi-Lin
supporting information, p. 4111 - 4115 (2019/06/07)
A protocol for highly enantioselective hydrogenation of racemic α-arylamino lactones with catalysis by site-specifically modified chiral spiro iridium complexes has been developed. With the optimized catalyst, racemic α-arylamino-γ-lactones and α-arylamino-δ-lactones could be hydrogenated to the corresponding chiral 2-amino diols with good to excellent enantioselectivities.
An efficient synthesis of optically pure (S)-2-functionalized 1,2,3,4-tetrahydroquinoline
Ding, Ke,Flippen-Anderson, Judy,Deschamps, Jeffrey R.,Wang, Shaomeng
, p. 1027 - 1029 (2007/10/03)
Using a copper-catalyzed coupling reaction of amino acid and aryl halide, followed by intramolecular cyclization of N-aryl-1-hydroxyl-3-propylamines under the Swern's condition as the key steps, (S)-2-hydroxymethyl-1,2,3,4- tetrahydroquinoline was synthesized as an example of optically pure 2-functionalized 1,2,3,4-tetrahydroquinolines.
