693790-86-2Relevant academic research and scientific papers
An efficient synthesis of optically pure (S)-2-functionalized 1,2,3,4-tetrahydroquinoline
Ding, Ke,Flippen-Anderson, Judy,Deschamps, Jeffrey R.,Wang, Shaomeng
, p. 1027 - 1029 (2004)
Using a copper-catalyzed coupling reaction of amino acid and aryl halide, followed by intramolecular cyclization of N-aryl-1-hydroxyl-3-propylamines under the Swern's condition as the key steps, (S)-2-hydroxymethyl-1,2,3,4- tetrahydroquinoline was synthesized as an example of optically pure 2-functionalized 1,2,3,4-tetrahydroquinolines.
