693794-61-5

Upstream product

• 108-24-7 acetic anhydride 
• 167558-54-5 2-(2,2-dibromo-vinyl)-phenylamine 
• 552-89-6 2-nitro-benzaldehyde 
• 75-36-5 acetyl chloride 
• 253684-24-1 1-(2,2-dibromovinyl)-2-nitrobenzene 
• 20939-77-9 2-acetamidobenzyl alcohol 
• 5344-90-1 2-Aminobenzyl alcohol 

Downstream Products

• 693794-65-9 1-[2-(4-methoxyphenyl)-1H-indol-1-yl]ethanone 
• 1006059-91-1 1-(2-o-tolylindol-1-yl)-ethanone 
• 1006059-90-0 1-[2-(4-acetylphenyl)-indol-1-yl]-ethanone 
• 78388-91-7 1-(2-phenylindol-1-yl)ethanone 
• 1527501-96-7 2,3,4-trimethoxy-6-tosyl-5,6-dihydroindolo[1,2-a]quinazoline 
• 1527502-02-8 C₂₅H₂₄N₂O₄S 
• 15937-04-9 5,6-dimethoxy-1-(4′-methylbenzenesulfonyl)indoline 
• 1527501-86-5 N-(1-acetyl-1H-indol-2-yl)-N-benzyl-4-methylbenzenesulfonamide 
• 1093942-84-7 N-benzyl-N-(1H-indol-2-yl)-4-methylbenzenesulfonamide 
• 1527501-85-4 C₂₄H₂₂N₂O₃S 
• 1527501-91-2 N-(1-acetyl-1H-indol-2-yl)-4-methyl-N-(4-methylbenzyl)benzenesulfonamide 
• 1527501-70-7 N-(1H-indol-2-yl)-4-methyl-N-(4-methylbenzyl)-benzenesulfonamide 
• 1527501-89-8 N-(1-acetyl-1H-indol-2-yl)-N-(4-methoxybenzyl)-4-methylbenzenesulfonamide 
• 1527501-71-8 N-(1H-indol-2-yl)-N-(4-methoxybenzyl)-4-methylbenzenesulfonamide 

Relevant academic research and scientific papers

Pd-Catalyzed Tandem Coupling Reaction of 2-gem-Dibromovinylanilines and N-Tosylhydrazones to Construct 2-(1-phenylvinyl)-indoles

A novel palladium(0)-catalyzed intermolecular coupling reaction of 2-gem-dibromovinylanilines and N-tosylhydrazones was reported to construct 2-(1-phenylvinyl)-indoles efficiently. The indole bearing 1, 1-disubstituted alkenes were obtained in one step wi

CuI-catalyzed coupling of gem-dibromovinylanilides and sulfonamides: An efficient method for the synthesis of 2-amidoindoles and indolo[1,2-a] quinazolines

A Cu(I)-catalyzed, intermolecular protocol for the synthesis of 2-amidoindoles and tetrahydroindolo[1,2-a]quinazolines in shorter time and high yields is reported. The key highlight of this disclosure is the formation of 2-amidoindole and tetrahydroindolo[1,2-a]quinazoline moieties directly from gem-dibromovinylanilides and sulfonamides in a one-pot fashion through the in situ formation of ynamides followed by a base-promoted intramolecular hydroamidation.

A highly selective tandem cross-coupling of gem-dihaloolefins for a modular, efficient synthesis of highly functionalized indoles

(Chemical Equation Presented) A highly efficient method of indole synthesis using gem-dihalovinylaniline substrates and an organoboron reagent was developed via a Pd-catalyzed tandem intramolecular amination and an intermolecular Suzuki coupling. Aryl, alkenyl, and alkyl boron reagents are all successfully employed, making for a versatile modular approach. The reaction tolerates a variety of substitution patterns on the aniline leading to indoles with group at C2-C7. The orthogonal approach of the sequential copper- and palladium-mediated synthesis of 1,2-diarylindoles exploited the wide availability of diverse organoboron reagents.

New synthesis of benzo[b]furan and indole derivatives from 1,1-dibromo-1-alkenes using a tandem Pd-assisted cyclization-coupling reaction

We report a new flexible method for the synthesis of 2-functionalized benzo[b]furans and indoles from readily available o-(2,2-dibromovinyl)-phenol, -aniline or -acetanilide using a tandem Pd-assisted cyclization-coupling reaction.