6938-19-8

Basic information

• Product Name: 6-hydroxy-5,7-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
• Synonyms: 4H-1-benzopyran-4-one, 6-hydroxy-5,7-dimethoxy-2-(4-methoxyphenyl)-; 6-Hydroxy-2-(4-methoxyphenyl)-5,7-dimethoxy-4H-1-benzopyran-4-one; 6-Hydroxy-4',5,7-trimethoxyflavone
• CAS NO: 6938-19-8
• Molecular Formula: C₁₈H₁₆O₆
• Molecular Weight: 328.316
• Mol File: 6938-19-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 556.5°C at 760 mmHg
• Flash Point: 205.3°C
• Density: 1.314g/cm³
• Vapor Pressure: 5.41E-13mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: 6-hydroxy-5,7-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-hydroxy-5,7-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one(6938-19-8)
• EPA Substance Registry System: 6-hydroxy-5,7-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one(6938-19-8)

Safety Data

• Hazardous Substances Data: 6938-19-8(Hazardous Substances Data)

Upstream product

• 15233-65-5 2,6-dimethoxy-1,4-hydroquinone 
• 93993-77-2 1-(3,6-dihydroxy-2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-propenone 
• 170234-78-3 1-(6-Hydroxy-2,4-dimethoxy-3-methoxymethoxy-phenyl)-3-(4-methoxy-phenyl)-propane-1,3-dione 
• 6962-57-8 3,6-dihydroxy-2,4-dimethoxyacetophenone 
• 7702-17-2 4-(acetyloxy)-3,5-dimethoxyphenyl acetate 
• 530-55-2 2,6-dimethoxy-p-quinone 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 10176-68-8 4-hydroxy-2,6-dimethoxy-3-(3-(4-methoxyphenyl)-3-oxopropanoyl)phenyl 4-methoxybenzoate 
• 104481-00-7 1-(6-hydroxy-2,4-dimethoxy-3-methoxymethoxyphenyl)-ethanone 

Downstream Products

• 170234-85-2 5,7-Dimethoxy-6-methoxymethoxy-2-(4-methoxy-phenyl)-chromen-4-one 
• 10176-71-3 ladanein 
• 1456770-94-7 C₁₈H₁₄O₆ 
• 529-53-3 scutellarein 
• 170234-94-3 Toluene-4-sulfonic acid 5,7-dimethoxy-6-methoxymethoxy-2-(4-methoxy-phenyl)-4-oxo-4H-chromen-3-yl ester 
• 170234-96-5 6-hydroxy-4',5,7-trimethoxy-3-(tosyloxy)flavone 
• 170235-01-5 Toluene-4-sulfonic acid 5,6,7-trihydroxy-2-(4-methoxy-phenyl)-4-oxo-4H-chromen-3-yl ester 
• 170234-68-1 3-Hydroxy-5,7-dimethoxy-6-methoxymethoxy-2-(4-methoxy-phenyl)-chromen-4-one 
• 170234-57-8 3,6-Dihydroxy-5,7-dimethoxy-2-(4-methoxy-phenyl)-chromen-4-one 
• 58942-16-8 3,5,6,7-tetrahydroxy-4'-methoxy flavone 
• 6563-66-2 5,6,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one 
• 67197-58-4 Acetic acid 5-hydroxy-7-methoxy-2-(4-methoxy-phenyl)-4-oxo-4H-chromen-6-yl ester 

Relevant articles and documents

A practical synthesis of the flavone, scutellarein

A practical and economical five-step synthesis of the flavone scutellarein has been achieved in 60% overall yield using the available and cheap 2,6-dimethoxy-1,4-benzoquinone as starting material. The reaction sequence involved reduction to the corresponding quinol, Friedel-Crafts acetylation, Claisen-Schmidt condensation with p-methoxybenzaldehyde, cyclisation and demethylation. The procedure is operationally simple and amenable to scale-up synthesis.

A practical and economical high-yielding, six-step sequence synthesis of a flavone: Application to the multigram-scale synthesis of ladanein

Herein we report a short and economic synthesis of the antiviral flavonoid lead ladanein (1). Ladanein is obtained from 2,6-dimethoxyquinone (11) in six steps with 51% overall yield. After a high-yielding reductive acetylation and Fries rearrangement, the

FLAVONE DERIVATIVES AND THEIR USE

The present invention relates to flavone derivatives and to compositions containing one or more of these flavone derivatives. The present invention further relates to fiavone derivatives or compositions for use in the treatment and/or prevention of a vira