69380-83-2

Basic information

• Product Name: N-(1-phenylethylidene)methanesulfonamide
• Synonyms: N-(1-phenylethylidene)methanesulfonamide
• CAS NO: 69380-83-2
• Molecular Weight: 197.258
• Mol File: 69380-83-2.mol

Chemical Properties

• CAS DataBase Reference: N-(1-phenylethylidene)methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-phenylethylidene)methanesulfonamide(69380-83-2)
• EPA Substance Registry System: N-(1-phenylethylidene)methanesulfonamide(69380-83-2)

Safety Data

• Hazardous Substances Data: 69380-83-2(Hazardous Substances Data)

Upstream product

• 10341-75-0 (E)-1-phenylethanone oxime 
• 18649-16-6 methanesulfinamide 
• 98-86-2 acetophenone 
• 3144-09-0 methanesulfonamide 

Downstream Products

• 221341-42-0 α-(methanesulfonylamido)ethylbenzene 
• 193482-26-7 (S)-N-(1-phenylethyl) methanesulfonamide 
• 316363-65-2 (R)-Ν-(1-phenylethyl)methanesulfonamide 

Relevant articles and documents

Direct Synthesis of Enolizable N-Sulfonyl Ketimines under Microwave Irradiation

N-sulfonyl imines are widely used as substrates for a range of transformations. Access to N-sulfonyl aldimines is straightforward through direct condensation between the parent aldehyde and the sulfonamide. However, this approach is not efficient for the

Asymmetric Stepwise Reductive Amination of Sulfonamides, Sulfamates, and a Phosphinamide by Nickel Catalysis

Asymmetric reductive amination of poorly nucleophilic sulfonamides was realized in the presence of nickel catalysts and titanium alkoxide. A wide range of ketones, including enolizable ketones and some biaryl ones, were converted into sulfonamides in excellent enantiomeric excess. The cyclization of sulfamates and intermolecular reductive amination of a diarylphosphinamide were also successful. Formic acid was used as a safe and economic surrogate of high-pressure hydrogen gas.

Asymmetric transfer hydrogenation reactions of: N -sulfonylimines by using alcohols as hydrogen sources

A palladium/zinc co-catalytic system was established and successfully utilized in the asymmetric transfer hydrogenation reactions of N-sulfonylimines with alcohols as hydrogen sources. Simple alcohols such as methanol, ethanol and benzyl alcohols are all

Pd/Zn(OTf)2 Co-Catalyzed Asymmetric Hydrogenation of Imines under Normal Pressure of Hydrogen

An efficient method for the asymmetric hydrogenation of cyclic and acyclic N-sulfonylimines co-catalyzed by Pd/Zn(OTf)2 using hydrogen gas under ambient pressure was developed. The methodology offers an easy access to generate chiral sulfonylam

Copper-Catalyzed Enantioselective Alkylation of Enolizable Ketimines with Organomagnesium Reagents

Inexpensive and readily available organomagnesium reagents were used for the catalytic enantioselective alkylation of enolizable N-sulfonyl ketimines. The low reactivity and competing enolization of the ketimines was overcome by the use of a copper–phosphine chiral catalyst, which also rendered the transformation highly chemoselective and enantioselective for a broad range of ketimine substrates.