69380-83-2Relevant academic research and scientific papers
Direct Synthesis of Enolizable N-Sulfonyl Ketimines under Microwave Irradiation
Ortiz, Pablo,Collados, Juan F.,Harutyunyan, Syuzanna R.
, p. 1247 - 1250 (2016)
N-sulfonyl imines are widely used as substrates for a range of transformations. Access to N-sulfonyl aldimines is straightforward through direct condensation between the parent aldehyde and the sulfonamide. However, this approach is not efficient for the
Asymmetric Stepwise Reductive Amination of Sulfonamides, Sulfamates, and a Phosphinamide by Nickel Catalysis
Zhao, Xiaohu,Xu, Haiyan,Huang, Xiaolei,Zhou, Jianrong Steve
supporting information, p. 292 - 296 (2018/12/13)
Asymmetric reductive amination of poorly nucleophilic sulfonamides was realized in the presence of nickel catalysts and titanium alkoxide. A wide range of ketones, including enolizable ketones and some biaryl ones, were converted into sulfonamides in excellent enantiomeric excess. The cyclization of sulfamates and intermolecular reductive amination of a diarylphosphinamide were also successful. Formic acid was used as a safe and economic surrogate of high-pressure hydrogen gas.
Pd/Zn(OTf)2 Co-Catalyzed Asymmetric Hydrogenation of Imines under Normal Pressure of Hydrogen
Gao, Yang,Yang, Fan,Pu, Dongdong,Laishram, Ronibala Devi,Fan, Ruifeng,Shen, Guoli,Zhang, Xuexin,Chen, Jingchao,Fan, Baomin
supporting information, p. 6274 - 6279 (2018/11/23)
An efficient method for the asymmetric hydrogenation of cyclic and acyclic N-sulfonylimines co-catalyzed by Pd/Zn(OTf)2 using hydrogen gas under ambient pressure was developed. The methodology offers an easy access to generate chiral sulfonylam
Asymmetric transfer hydrogenation reactions of: N -sulfonylimines by using alcohols as hydrogen sources
Yang, Fan,Chen, Jingchao,Shen, Guoli,Zhang, Xuexin,Fan, Baomin
supporting information, p. 4963 - 4966 (2018/05/23)
A palladium/zinc co-catalytic system was established and successfully utilized in the asymmetric transfer hydrogenation reactions of N-sulfonylimines with alcohols as hydrogen sources. Simple alcohols such as methanol, ethanol and benzyl alcohols are all
Copper-Catalyzed Enantioselective Alkylation of Enolizable Ketimines with Organomagnesium Reagents
Ortiz, Pablo,Collados, Juan F.,Jumde, Ravindra P.,Otten, Edwin,Harutyunyan, Syuzanna R.
supporting information, p. 3041 - 3044 (2017/03/14)
Inexpensive and readily available organomagnesium reagents were used for the catalytic enantioselective alkylation of enolizable N-sulfonyl ketimines. The low reactivity and competing enolization of the ketimines was overcome by the use of a copper–phosphine chiral catalyst, which also rendered the transformation highly chemoselective and enantioselective for a broad range of ketimine substrates.
