6939-13-5Relevant academic research and scientific papers
Synthesis, characterization, spectroscopy, cytotoxic activity and molecular dynamic study on the interaction of three palladium complexes of phenanthroline and glycine derivatives with calf thymus DNA
Ajloo, Davood,Eslami Moghadam, Mahboube,Ghadimi, Khadijeh,Ghadamgahi, Maryam,Saboury, Ali Akbar,Divsalar, Adeleh,Sheikhmohammadi, Minoo,Yousefi, Khalil
, p. 144 - 160 (2015/03/31)
The interaction of three novel synthesized complexes of [Pd(phen)(R-gly)]NO3, where R-gly is methyl-, propyl-, and amyl-glycine; and phen is 1,10-phenanthroline were synthesized and characterized by spectroscopic methods. The interaction of ct-
PRO-DRUG COMPOUNDS
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Page/Page column 23-24, (2014/01/18)
A compound of formula (I), or a pharmaceutically acceptable salt thereof: wherein Z1, Z2, and Z3, Q, R2, A, and R1 are as defined in the claims.
Pro-drug Compounds
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Paragraph 0176; 0177, (2014/02/15)
A compound of formula (I), or a pharmaceutically acceptable salt thereof: The compound is used in pharmaceutical compositions and in a method of treatment of a disease or medical condition which benefits from inhibition of gap junction activity by administering to a subject suffering from such disease or condition.
Polypeptoids from n-substituted glycine n-carboxyanhydrides: Hydrophilic, hydrophobic, and amphiphilic polymers with poisson distribution
Fetsch, Corinna,Grossmann, Arlett,Holz, Lisa,Nawroth, Jonas F.,Luxenhofer, Robert
experimental part, p. 6746 - 6758 (2012/03/10)
Preparation of defined and functional polymers has been one of the hottest topics in polymer science and drug delivery in the recent decade. Also, research on (bio)degradable polymers gains more and more interest, in particular at the interface of these t
Synthesis of Strombine. A New Method for Monocarboxymethylation of Primary Amines
Kihlberg, Jan,Bergman, Rolf,Wickberg, Boerje
, p. 911 - 916 (2007/10/02)
Many common methods for monocarboxymethylation of primary amines give various amounts of dialkylated by-products.In this work the reaction of two equivalents of glyoxilic acid with representative primary aliphatic and aromatic amines, as well as with amino acids and a dipeptide, is shown to give only the N-(carboxymethyl)-N-formyl derivative of the amine under mild conditions in carboxylic acid solvents.Hydrolysis then produces the monocarboxymethylated primary amine in good to exellent overall yield.Proof that the intermediate product is not obtained via the Leuckart reaction is given.
