165607-76-1

Basic information

• Product Name: N-PROPYL-N-BOC-GLYCINE
• Synonyms: N-PROPYL-N-BOC-GLYCINE;(tert-Butoxycarbonyl-propyl-amino)-acetic acid
• CAS NO: 165607-76-1
• Molecular Formula: C10H19NO4
• Molecular Weight: 217.27
• Mol File: 165607-76-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 318.4±21.0 °C(Predicted)
• Appearance: /
• Density: 1.091±0.06 g/cm3(Predicted)
• PKA: 4.03±0.10(Predicted)
• CAS DataBase Reference: N-PROPYL-N-BOC-GLYCINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-PROPYL-N-BOC-GLYCINE(165607-76-1)
• EPA Substance Registry System: N-PROPYL-N-BOC-GLYCINE(165607-76-1)

Safety Data

• Hazardous Substances Data: 165607-76-1(Hazardous Substances Data)

Upstream product

• 107-10-8 propylamine 
• 34619-03-9 tert-butyldicarbonate 
• 5949-29-1 citric acid monohydrate 
• 79-08-3 bromoacetic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 6939-13-5 2-(propylamino)acetic acid hydrochloride 
• 4530-20-5 BOC-glycine 
• 107-08-4 1-iodo-propane 
• 1178666-01-7 C₁₂H₂₃NO₄ 

Downstream Products

• 1532591-82-4 (3S,4S)-6-acetyl-4-[(3-chloro-4-fluorobenzene)amido]-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-3-yl 2-{[(tert-butoxy)carbonyl](propyl)amino}acetate 
• 1532591-81-3 (3S,4S)-6-acetyl-4-[(3-chloro-4-fluorobenzene)amido]-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-3-yl 2-(propylamino)acetate hydrochloride 

Relevant articles and documents

PRO-DRUG COMPOUNDS

A compound of formula (I), or a pharmaceutically acceptable salt thereof: wherein Z1, Z2, and Z3, Q, R2, A, and R1 are as defined in the claims.

NOVEL THIOPHENECARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF

The object of the present invention is to provide a compound having a glucokinase-activating effect. A pharmaceutical composition comprising a compound represented by the general formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient: wherein X means a nitrogen atom or CR6, wherein R6 means a hydrogen atom or a halogen atom; R1 means a hydrogen atom, a C1-C6 alkyl group, a C1-C6 alkoxy group or a C1-C6 alkylthio group; R2 means a hydrogen atom or a fluorine atom; R3 means a hydrogen atom or a C1-C6 alkyl group; and one of R4 and R5 means a hydrogen atom or a C1-C6 alkyl group, and the other means a C1-C6 alkylenecarboxylic acid, a C1-C6 alkylsulfonyl group, a C1-C6 alkylcarbonyl group, or CONH2.

Amino substituted aryloxybenzylpiperidine derivatives

This invention is directed to Amino substituted Aryloxybenzylpiperidine derivatives which are ligands at the MCH1 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by admixing a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject a therapeutically effective amount of a compound of the subject invention. This invention also provides a method of treating a subject suffering from obesity which comprises administering to the subject a therapeutically effective amount of a compound of the subject invention.