694-56-4Relevant academic research and scientific papers
Deprotonation of 1-(carbethoxyalkyl)pyridinium halides with strong N-bases
Dega-Szafran, Zofia,Schroeder, Grzegorz,Szafran, Miroslaw
, p. 39 - 46 (2007/10/03)
The rate constants were measured for deprotonation of 1-(carbethoxymethyl)pyridinium chloride and 1-(2-carbethoxyethyl)pyridinium bromide with strong bases (DBU, MTBD, TBD and P2-Et) in acetonitrile. The UV spectra and semiempirical calculations are consistent with an ylide structure of the deprotonated species. The ylides obtained slowly decompose, and the reaction products were identified by 1H NMR spectroscopy; 1-(carbethoxymethyl)pyridinium chloride gives N-methylpyridinium cation and ethanol and 1-(2-carbethoxyethyl)pyridinium bromide converts to pyridine and ethyl acrylate. Copyright
NOUVELLE SYNTHESE SIMPLE DE NUCLEOSIDE PHOSPHOROTHIOLATE
Asseline, U.,Thuong, N. T.
, p. 847 - 850 (2007/10/02)
The O,S-dimethylphosphorochloridate 10 reacts with 5'-O-monomethoxytritylthymidine 11 in pyridine giving nucleoside-3'-thiolophosphodiester 13 in high yields ; in acetonitrile and in the presence of 1-methylimidazole, this reaction leads to the nucleoside-3'-phosphotriester 14 without formation of diester 13.From the latter, the Tp and TpT have been prepared.
