6940-23-4

Usage

Type of compound

Synthetic organic compound

Use

Herbicide

Mode of action

Inhibits photosynthesis by interfering with the electron transport chain in chloroplasts

Target plants

Broadleaf and grassy weeds

Crops

Peanuts, soybeans, potatoes

Additional applications

Non-crop areas such as roadsides and industrial sites for weed control

Classification

Restricted use pesticide

Environmental hazards

Toxicity to aquatic organisms

Health hazards

Potential carcinogenicity in humans

Importance of handling

Proper handling and application are essential to minimize negative impacts on the environment and human health

Upstream product

• 88-10-8 N,N-diethylcarbamyl chloride 
• 95-53-4 o-toluidine 
• 614-68-6 2-tolyl isocyanate 
• 109-89-7 diethylamine 
• 201230-82-2 carbon monoxide 
• 88-72-2 1-methyl-2-nitrobenzene 
• 13939-06-5 molybdenum hexacarbonyl 
• 97600-23-2 3,3-diethyl-1-(2-tolyl)-1-nitrosourea 

Downstream Products

• 1188355-31-8 4-(3,3-diethylureido)-3-methyl-benzenesulfonyl chloride 
• 36719-44-5 3,3-diethyl-1-(o-tolyl)triaz-1-ene 
• 97600-23-2 3,3-diethyl-1-(2-tolyl)-1-nitrosourea 

Relevant academic research and scientific papers

Pd/C-catalyzed reductive carbonylation of nitroaromatics for the synthesis of unsymmetrical ureas: One-step synthesis of neburon

A Pd/C catalyzed reductive carbonylation of nitroarenes for the synthesis of unsymmetrical ureas has been developed. Using inexpensive and stable nitroarenes as the substrates, a series of unsymmetrical ureas were produced in moderate to good yields. A range of functional groups including thioethers, halides and vinyl were compatible with this reaction. As a heterogeneous catalyst, Pd/C was recycled and reused four times without losing activity. Notably, urea-based herbicide neburon was prepared in 64% yield under our standard conditions.

NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

The present invention relates to novel 3-aminoalkyl-1,3-dihydro-2H-indol-2-one derivatives, to their preparation and to their therapeutic application. The compounds of the present invention correspond to the formula (I): in which the variables are as set forth in the specification. These compounds exhibit a strong affinity and a high selectivity for human arginine-vasopressin (AVP) V1a receptors and some compounds additionally exhibit a strong affinity for AVP V1b receptors.

Synthesis of unsymmetrical ureas by sulfur-assisted carbonylation with carbon monoxide and oxidation with molecular oxygen under mild conditions

With ambient pressure of carbon monoxide and oxygen at room temperature, N,N-dialkyl-N′-arylureas were selectively accessible from secondary amines, aromatic amines, and sulfur in good to excellent yields. For example, N-butyl-N-methyl-N′-(3,4-dichlorophenyl)urea, which is used as a herbicide (neburon), was afforded successfully from butylmethylamine (2 equiv), 3,4-dichloroaniline (1 equiv) and sulfur (1 equiv) in 79% (21.8 g) yield using carbon monoxide (0.1 MPa) and oxygen (0.1 MPa) at 20°C in DMF. Georg Thieme Verlag Stuttgart.