69423-57-0Relevant academic research and scientific papers
Stereoselective catalytic synthesis of P-stereogenic oxides via hydrogenative kinetic resolution
Fernández-Pérez, Héctor,Vidal-Ferran, Anton
, p. 7019 - 7023 (2019)
A highly stereoselective catalytic method for the preparation of structurally diverse P-stereogenic oxides has been developed. The approach relies on the ability of rhodium complexes derived from an enantiopure P-OP ligand to kinetically resolve racemic α,β-unsaturated phosphane oxides by hydrogenation of the C= C motif and formation of highly enantioenriched (or even enantiopure) P-stereogenic oxides. The practicality of the methodology has been demonstrated by the preparation of potentially functional P-chiral molecules for catalytic enantioselective synthesis.
GRIGNARD REACTION OF 2-PHENYL-TETRAHYDROPYRROLO-1,3,2-OXAZAPHOSPHOLES, OBSERVATION OF THE STEREOSPECIFIC INVERSION OF CONFIGURATION
Koizumi, Toru,Yanada, Reiko (nee Ishizaka),Takagi, Hiroyasu,Hirai, Hajime,Yoshii, Eiichi
, p. 571 - 572 (2007/10/02)
Grignard reaction of bicyclic oxazaphospholes proceeded with inversion of configuration to provide chiral phosphinic esters of known absolute configurations.
