694496-27-0

Upstream product

• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 220353-22-0 4-amino-2,6-difluorophenol hydrochloride 

Downstream Products

• 1273148-12-1 2,6-difluoro-4-(1H-pyrrol-1-yl)phenyl 3-methoxybenzoate 
• 1273148-11-0 2,6-difluoro-4-(1H-pyrrol-1-yl)phenyl 4-methoxybenzoate 
• 1273148-16-5 (1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-2-yl)(4-methoxyphenyl)methanone 
• 1273148-13-2 (1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl)(4-methoxyphenyl)methanone 
• 1273148-17-6 (1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-2-yl)(3-methoxyphenyl)methanone 
• 1273148-14-3 (1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl)(3-methoxyphenyl)methanone 
• 1422283-03-1 C₁₇H₉BrF₃NO₂ 
• 1422283-01-9 C₁₇H₉BrF₃NO₂ 
• 1422283-02-0 ([1,1’-biphenyl]-4-yl)[1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]methanone 
• 1422283-00-8 ([1,1’-biphenyl]-4-yl)[1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-2-yl]methanone 
• 1422282-99-2 C₁₂H₆F₅NO₂ 
• 694496-28-1 benzoic acid 2,6-difluoro-4-pyrrol-1-ylphenyl ester 

Relevant academic research and scientific papers

Clauson-kaas-type synthesis of pyrrolyl-phenols, from the hydrochlorides of aminophenols, in the presence of nicotinamide

A facile Clauson-Kaas-type pyrrolyl-phenol synthesis has been achieved in the presence of nicotinamide, which is inexpensive and nontoxic. The starting material is aminophenol hydrochloride. This is advantageous in certain cases because it is the only isolatable form of the corresponding aminophenol.

[1-(3,5-Difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone as a Bioisostere of a Carboxylic Acid Aldose Reductase Inhibitor

[1-(3,5-Difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone (6) was synthesized as a putative bioisostere of the known aldose reductase (AR) inhibitor (3-benzoylpyrrol-1-yl)acetic acid (I). It was found that 6 is approximately 5 times more potent as