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6945-68-2 Usage

Chemical Properties

yellow-brown crystalline powder


2-Amino-5-bromo-3-nitropyridine may be used in the preparation of azaquinoxalinedione.

General Description

2-Amino-5-bromo-3-nitropyridine is formed as intermediate in the synthesis of 2,3-diaminopyridine.

Check Digit Verification of cas no

The CAS Registry Mumber 6945-68-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,4 and 5 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6945-68:
132 % 10 = 2
So 6945-68-2 is a valid CAS Registry Number.

6945-68-2 Well-known Company Product Price

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  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (A14985)  2-Amino-5-bromo-3-nitropyridine, 97%   

  • 6945-68-2

  • 1g

  • 348.0CNY

  • Detail
  • Alfa Aesar

  • (A14985)  2-Amino-5-bromo-3-nitropyridine, 97%   

  • 6945-68-2

  • 5g

  • 1197.0CNY

  • Detail
  • Alfa Aesar

  • (A14985)  2-Amino-5-bromo-3-nitropyridine, 97%   

  • 6945-68-2

  • 25g

  • 5078.0CNY

  • Detail
  • Aldrich

  • (376884)  2-Amino-5-bromo-3-nitropyridine  97%

  • 6945-68-2

  • 376884-1G

  • 314.73CNY

  • Detail
  • Aldrich

  • (376884)  2-Amino-5-bromo-3-nitropyridine  97%

  • 6945-68-2

  • 376884-5G

  • 993.33CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name 2-Amino-5-bromo-3-nitropyridine

1.2 Other means of identification

Product number -
Other names 5-Bromo-3-Nitro-2-Pyridinamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6945-68-2 SDS

6945-68-2Relevant articles and documents

Alkylsulfonamide-containing quinazoline derivatives as potent and orally bioavailable PI3Ks inhibitors

Hei, Yuan-Yuan,Zhang, San-Qi,Feng, Yifan,Wang, Jin,Duan, Weiming,Zhang, Hao,Mao, Shuai,Sun, Haopeng,Xin, Minhang

, (2019/06/08)

Phosphoinositide 3-kinases (PI3Ks) are regarded as promising targets for treatment of various cancers due to their roles in regulating cell proliferation, differentiation, migration, and survival. Here we report our efforts to develop potent and orally bioavailable PI3K inhibitors for the treatment of cancers. The alkylsulfonamide-containing quinazoline derivatives A1–A18 significantly inhibited PI3Kα, and cell proliferation among HCT-116, MCF-7 and SU-DHL-6 cell lines. The optimal compound A1 displayed potent inhibitory activity against PI3Kα (IC50 = 4.5 nM), PI3Kβ (IC50 = 4.5 nM), PI3Kγ (IC50 = 4.5 nM), PI3Kδ (IC50 = 4.5 nM) and significantly inhibited the growth of HCT-116, MCF-7 and SU-DHL-6 cell lines with IC50 values of 0.82 μM, 0.99 μM and 0.19 μM, respectively. Western blot analysis demonstrated A1 significantly suppressed the phosphorylation of AKTS473 in a dose-dependent manner. Furthermore, A1 could markedly inhibit cancer growth at the dose of 25 mg/kg in nude mouse HCT-116 xenograft model in vivo without causing significant weight loss or toxicity.

New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons

Sapegin, Alexander V.,Kalinin, Stanislav A.,Smirnov, Alexey V.,Dorogov, Mikhail V.,Krasavin, Mikhail

, p. 1077 - 1083 (2014/01/23)

A streamlined synthetic methodology towards novel tetracyclic 1,4-oxazepines from readily available precursors is described. The compounds, designed as more soluble version of the earlier described, poorly soluble dibenzo[b,f][1,4]oxazepines, were obtained in high yields and as a single regioisomer as a result of three tandem chemical events - nucleophilic aromatic substitution, Smiles rearrangement and denitrocyclization.

Synthesis and testing of new end-functionalized oligomers for molecular electronics

Flatt, Austen K.,Dirk, Shawn M.,Henderson, Jay C.,Shen, Dwanleen E.,Su, Jie,Reed, Mark A.,Tour, James M.

, p. 8555 - 8570 (2007/10/03)

Several new classes of oligomers have been synthesized with functionalities designed to aid in the understanding of molecular device behavior, specifically when molecules are interfaced between proximal electronic probes. The compounds synthesized are series of azobenzenes, bipyridines and oligo(phenylene vinylene)s that bear acetyl-protected thiols for ultimate attachment to metallic surfaces. Some initial electrochemical and solid-state test results are also reported.

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