69457-08-5

Upstream product

• 95-64-7 4-amino-o-xylene 

Downstream Products

• 18800-53-8 3,4-dimethylthiophenol 
• 13636-53-8 3,4-dimethylphenylhydrazine 
• 899242-94-5 methyl 4-({1-(3,4-dimethylphenyl)-5-[(furan-2-ylcarbonyl)amino]-1H-pyrazole-4-carbonyl}amino)benzoate 
• 64346-07-2 bis-(3,4-dimethyl-phenyl)-disulfide 
• 104216-46-8 3-(3,4-dimethyl-phenylsulfanyl)-propionic acid 
• 93599-27-0 [1-[5-(3,4-Dimethyl-phenyl)-thiophen-2-yl]-eth-(E)-ylideneaminooxy]-acetic acid 
• 93599-25-8 1-[5-(3,4-Dimethyl-phenyl)-thiophen-2-yl]-ethanone O-(2-diethylamino-ethyl)-oxime 
• 93599-26-9 1-[5-(3,4-Dimethyl-phenyl)-thiophen-2-yl]-ethanone O-allyl-oxime 
• 93599-34-9 1-[5-(3,4-Dimethyl-phenyl)-thiophen-2-yl]-ethanone oxime 

Relevant academic research and scientific papers

Synthesis of new 1-(3,4-dimethylphenyl)-1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one derivatives

New substituted pyrazolo[3,4-d]pyrimidin-4-ones have been synthesized as a result of a series of transformations including hydrolysis of ethyl 5-amino-1H-pyrazole-4-carboxylates, cyclization of the carboxylic acids thus obtained to pyrazolo[3,4-d][1,3]oxazin-4(1H)-ones, and treatment of the latter with substituted anilines. The final pyrazolo[3,4-d]pyrimidin-4-one derivatives can also be synthesized from 5-(arylamido)-1H-pyrazole-4-carboxylic acids in the presence of a catalytic amount of anhydrous zinc(II) chloride.

Synthesis and antimicrobial activity of 2-(4-formyl-3-pyrazolyl)-3- phenylindoles

Vilsmeier-Haack reagent (POCl3-DMF) on reaction with hydrazones 3a-i derived from 2-acetyl-3-phenylindoles 2a-c furnishes 2-(4-formyl-3- pyrazolyl)-3-phenylindoles 4a-i. The structures of these compounds have been established on the basis of their elemental analyses and spectral (IR, 1H NMR) data. All the pyrazole derivatives 4a-i and their azines 5a-i have been tested for their antimicrobial and antifungal activities.

Synthesis and Pharmacology of Some New Oxime Ethers Derived from 2-Acetyl-5-arylthiophenes

Several new 5-arylthiophene-2-acetoxime ethers (1-28) have been synthesised and screened for their pharmacological activities.Some of these compounds possess moderate antiinflammatory and mild CNS depressant activities.The intermediate 2-acetyl-5-(p-ethyl/p-iso-propyl/3,4-dimethylphenyl)thiophenes (1b-d) and their oximes (IIb-d) have been reported for the first time.