6946-08-3Relevant academic research and scientific papers
Aza-Rubottom Oxidation: Synthetic Access to Primary α-Aminoketones
Zhou, Zhe,Cheng, Qing-Qing,Kürti, László
supporting information, (2019/02/14)
An aza analogue of the Rubottom oxidation is reported. This facile transformation takes place at ambient temperature and directly converts silyl enol ethers to the corresponding primary α-aminoketones. The use of hexafluoroisopropanol (HFIP) as the solven
RADICAL STABILISATION: SYNTHESIS AND DECOMPOSITION OF A β-KETODIAZENE
Zavalsky, Robert C.,Lisiak, Michael,Kovacic, Peter,Luedtke, Al,Timberlake, Jack W.
, p. 425 - 428 (2007/10/02)
The synthesis and decomposition of bis(1,1-dimethyl-2-oxo-2-phenylethyl)diazene (7e) is described.The presence of a carbonyl group adjacent to a radical center greatly enhances the radical stability.
Cyclization of Non-tautomerizing anti-α-Aminohydrazones into N-Aminoimidazolidines
Gnichtel, Horst,Belkien, Lutz,Totz, Wolfgang,Wawretschek, Lothar
, p. 1016 - 1027 (2007/10/02)
The α-aminoisobutyrophenone phenylhydrazones 3a-h have been prepared and their anti-configuration determined UV spectroscopically.Cyclization of 3 with phosgene yields the hexahydrotetrazine derivatives 5 which react with water to give the 3-anilino-4-hyd
HYDROBORATION D'AZIRIDINES ETHYLENIQUES. SYNTHESE D'AZA-1 BICYCLO ALCANES
Chaabouni, Refaat,Laurent, Andre,Marquet, Bernard
, p. 877 - 885 (2007/10/02)
Hydroboration of aziridines having a β or γ-double bond 3b, 3c, 4b, 7c and 8 yields after oxydation, the expected hydroxy aziridines 11b, 11c, 12b, 13 and 14, which were cyclized by reaction with PPh3/Br2 to give 1-aza bicycloalkanes 23b, 24b, 25c, 26 and 27.The hydroboration of 2-vinyl aziridines 3a, 4a and 7a give Z-allylic amines 16aZ, 17aZ and 18Z.The use of 9-BBN or 2-vinyl substituated aziridines provides the β-hydroxy aziridines 19, 20 and 21.
