210898-28-5Relevant academic research and scientific papers
DAST-mediated cyclization of α,α-disubstituted-α- acylaminoketones: Efficient and divergent synthesis of unprecedented heterocycles
Bigot, Aurelien,Blythe, Judith,Pandya, Chirag,Wagner, Trixie,Loiseleur, Olivier
, p. 192 - 195 (2011/03/20)
The design of a new potent nonsteroidal ecdysone agonist led to the discovery of a diethylaminosulfur trifluoride (DAST)-mediated cyclization of α,α-disubstituted-α-acylaminoketones. The resulting fluorooxazolines can be ring-opened or selectively substit
