69466-52-0Relevant academic research and scientific papers
Sequential Michael Addition and Enamine-Promoted Inverse Electron Demanding Diels-Alder Reaction upon 3-Vinyl-1,2,4-triazine Platforms
Lorion, Magali,Guillaumet, Gérald,Brière, Jean-Fran?ois,Suzenet, Franck
supporting information, p. 3154 - 3157 (2015/06/30)
An original one-pot Michael addition-ihDA/rDA sequence was achieved from 3-vinyl-1,2,4-triazine platforms used as unprecedented Michael acceptors. This sequence provides a novel access to functionalized [2,3]-fused pyridine derivatives via a unique enamin
C-H-Functionalization of 1,2,4-triazines: Oxidation and elimination pathways of aromatization of σh-adducts
Berezin,Rusinov,Charushin
, p. 1359 - 1363 (2015/03/14)
An approach to the synthesis of 1,2,4-triazine thienyl and furyl derivatives through the reaction of aromatic nucleophilic substitution of hydrogen was suggested. Oxidation and cine-elimination pathways of aromatization of the intermediate σH-a
Pharmacologically active substituted 1,2,4-triazines
-
, (2008/06/13)
Substituted 1,2,4-triazines, compositions thereof and methods of using same are described. The compounds of the invention exhibit a wide range of pharmacological activity including anti-inflammatory, analgesic, anti-pyretic, hypotensive and central nervous system effects.
