6949-73-1

Usage

Uses

Used in Pharmaceutical Industry:
2-HYDROXY-9-FLUORENONE is used as a reactant for the one-pot synthesis of aryl substituted aurones, which are important compounds in the development of pharmaceuticals due to their potential biological activities.
Used in Material Science:
2-HYDROXY-9-FLUORENONE is used as a reactant for tuning the HOMO-LUMO levels of 9-fluorenone scaffolds. This is crucial in the development of new materials with specific electronic properties, such as organic semiconductors and light-emitting diodes.
Used in Synthesis of Molecular Motors:
2-HYDROXY-9-FLUORENONE is used as a reactant in O-methylation reactions for the synthesis of second-generation light-driven rotary molecular motors. These molecular motors have potential applications in nanotechnology and materials science.
Used in Organic Chemistry:
2-HYDROXY-9-FLUORENONE is used in reactions with aluminum, gallium compounds, and methylquinolines, which are important for the synthesis of various organic compounds with diverse applications.
Used in Calixarene Synthesis:
2-HYDROXY-9-FLUORENONE is used as a reactant in the synthesis of acridinyland fluorenylidenehydrazido calixarenes. Calixarenes are a class of macrocyclic compounds with potential applications in supramolecular chemistry, drug delivery, and chemical sensing.
Used in Organic Synthesis:
2-HYDROXY-9-FLUORENONE is used as a reactant in acetylation reactions for the synthesis of acetates, which are important intermediates in the production of various chemicals and pharmaceuticals.

InChI:InChI=1/C13H8O2/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)12(10)7-8/h1-7,14H

Upstream product

• 2443-58-5 2-hydroxyfluorene 
• 3096-57-9 2-amino-9-fluorenone 
• 52108-18-6 4-hydroxy-biphenyl-2-carboxylic acid 
• 23668-26-0 cis-1,2,3,4,4a,9a-Hexahydrofluoren-2,9-dion 
• 57247-77-5 9-oxo-9H-2-fluorenyl acetate 
• 52008-73-8 4-oxo-1-phenyl-2,5-cyclohexadiene-1-carboxylic acid ethyl ester 
• 34265-59-3 ethyl 4-hydroxybiphenyl-2-carboxylate 
• 4192-77-2 ethyl cinnamate 
• 87199-18-6 3-hydroxyphenylboronic acid 
• 98-88-4 benzoyl chloride 
• 3096-56-8 2-bromofluoren-9-one 
• 486-25-9 9-fluorenone 

Downstream Products

• 64352-53-0 3-hydroxyphenanthridin-6(5H)-one 
• 64352-54-1 8-hydroxy-5H-phenanthridin-6-one 
• 586345-82-6 5-benzyloxy-1-methyl-2-{[(9-oxo-9H-fluoren-2-yl)oxy]methyl}-1H-pyridin-4-one 
• 2443-58-5 2-hydroxyfluorene 
• 57247-77-5 9-oxo-9H-2-fluorenyl acetate 
• 54099-24-0 Triethyl-[2-(9-oxo-9H-fluoren-2-yloxy)-ethyl]-ammonium; iodide 
• 1245575-08-9 2-(3,4,5-tris(octadecyloxy)-cyclohexylmethoxy)-9-fluorenone 
• 1367249-34-0 2-(12-docosyloxydodecanoxy)-9-(3-fluorophenyl)-9-fluorenol 
• 1245574-87-1 2-(12-docosyloxydodecanoxy)-9-(3-fluorophenyl)-9-bromofluorene 
• 1245575-95-4 C₆₄H₉₂ClNO₆ 

Relevant academic research and scientific papers

Spirooxazine photochromic compound changing from colorless to blue as well as preparation method and application of spirooxazine photochromic compound

The invention discloses a spirooxazine photochromic compound changing from colorless to blue as well as a preparation method and application of the spirooxazine photochromic compound, and belongs to the technical field of organic functional materials. The objective of the invention is to develop and meet aesthetic needs of customers. The invention discloses a photochromic compound with high outdoor stability and a formula of a coating thereof. The spirooxazine photochromic compound changing from colorless to blue prepared by the invention has the advantages of high photoresponse speed, high fading speed, stable performance in a closed-loop state in outdoor use, low-price and easily available synthetic raw materials and high operability of a synthetic process, and meets the market aestheticrequirements.

MANUFACTURING METHOD OF HYDROXYFLUORENONES

PROBLEM TO BE SOLVED: To provide a novel manufacturing method of hydroxyfluorenones. SOLUTION: By the method, a compound represented by the following formula (2) is manufactured by reacting a compound (A) represented by the following formula (1) and at least one kind of metal hydroxide (B) selected from alkali metal hydroxides, alkali earth metal hydroxides, and a hydrates thereof in presence of at least one kind of Periodic Table 11 group element-containing material (C) selected from simple substance of Periodic Table 11 group elements and compound containing the element, and a compound (D) having N,N'-substituted oxamide skeleton. Ar1 and Ar2 represent each independently an arylene ring, X represent each independently a halogen atom, R1 each independently represents a substituent, m1 and m2 represent integers of 0 or more, n1 and n2 represent integers of 0 or more and n1+n2 is 1 or more. SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT

Synthesis of Phenols: Organophotoredox/Nickel Dual Catalytic Hydroxylation of Aryl Halides with Water

A highly effective hydroxylation reaction of aryl halides with water under synergistic organophotoredox and nickel catalysis is reported. The OH group of the resulting phenols originates from water, following deprotonation facilitated by an intramolecular base group on the ligand. Significantly, aryl bromides as well as less reactive aryl chlorides served as effective substrates to afford phenols with a wide range of functional groups. Without the need for a strong inorganic base or an expensive noble-metal catalyst, this process can be applied to the efficient preparation of diverse phenols and enables the hydroxylation of multifunctional pharmaceutically relevant aryl halides.

Palladium-catalyzed synthesis of fluoreones from bis(2-bromophenyl)methanols

A palladium-catalyzed synthesis method of fluorenones has been developed. A variety of bis(2-bromophenyl)methanols could undergo the reaction smoothly in the presence of Pd(OAc)2, affording a series of fluorenones in moderate to good yields (two steps). Mechanistic studies reveal that the reaction might be triggered by oxidation of alcohol followed by intramolecular reductive coupling.

Expeditious Assembly of Fluorenones through Domino Reactions of Benzoyl Chlorides with Arylboronic Acids Catalyzed by ONO Pincer-like Palladium(II) Complexes

A new set of palladium(II) complexes featuring ONO pincer-type ligands were synthesized and utilized as efficient homogeneous catalysts for the domino reactions of benzoyl chlorides with arylboronic acids to yield a library of fluorenones. The titled reaction proceeded smoothly in H2O/MeOH media at a low catalyst loading (0.1 mol %) under mild reaction conditions in an open flask, and the catalyst could be reused over six consecutive runs. To validate the currently developed methodology for industrial-level applications, a gram-scale synthesis was done. Advantageously, the present protocol does not require any external oxidant, additives, or phase-transfer agents.

Asymmetry in molecular ordering in the nematic phase: DMR study

Deuterium nuclear magnetic resonance (2H-NMR) was performed on the rigid perdeuterated fluorene segment of the compound 2-fluorenyl-4'-tetradecyloxy benzoate (FLOC 14-d9) tounambiguously measure the order parameter U which reflects the degree of asymmetric ordering of the molecule in the nematic liquid crystalline phase.Measurements of U showed this parameter to be finite at all temperatures in the nematic phase indicative of the uniaxial phase U2 described in the Allender-Lee generalized Landau theory.Mixtures of FLOC 14-d9 with compounds consisting of molecules more cylindrical in shape were also studied to examine their effect on the parameter U.Other parameters such as the degree of order S and the orientation of the principal axes of the Maier-Saupe order matrix were measured and are discussed.