6950-53-4

Usage

Uses

Used in Pesticide Manufacturing:
2-methylsulfanylethanamine is used as a key ingredient for the synthesis of various pesticides, contributing to the development of effective crop protection products.
Used in Rubber Processing:
2-methylsulfanylethanamine is used as a processing aid in the rubber industry, enhancing the properties of rubber products and facilitating their manufacturing process.
Used in Molecular Biology:
2-methylsulfanylethanamine is used as a reagent in molecular biology research, aiding in the study of biological processes and the development of new techniques and applications.
Used in Research Labs:
2-methylsulfanylethanamine is used as a chemical intermediate in various laboratory experiments, contributing to the advancement of scientific knowledge and the discovery of new compounds.
Used in Paper and Textile Industries:
2-methylsulfanylethanamine is used as a chemical agent in the paper and textile industries, improving the quality and performance of these materials.

Upstream product

• 174360-08-8 tert-butyl (2-(methylthio)ethyl)carbamate 
• 18542-42-2 (2-aminoethyl)methylsulfide 

Downstream Products

• 1361456-15-6 C₆H₅-C{NH(CH₂)2SMe}=NC₆H₅ 
• 1275595-87-3 6-(5-((2-(methylthio)ethylamino)methyl)furan-2-yl)-N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-4-quinazolinamine 
• 174360-08-8 tert-butyl (2-(methylthio)ethyl)carbamate 
• 1442655-93-7 C₂₆H₃₈N₄S₂ 

Relevant academic research and scientific papers

Novel anthranilic diamide insecticides: Design, synthesis, and insecticidal evaluation

Three series of new anthranilic diamide derivatives containing sulfide, N-cyanomethylsulfilimine, and N-cyanomethylsulfoximine groups were designed and synthesized by coupling the active substructures of anthranilic diamides and sulfoxaflor. The structures of the synthesized compounds were confirmed by infrared spectroscopy, 1H and 13C NMR, and elemental analysis. Several unique structural characteristics were revealed via the crystal structure analysis of compound N-(2-(2-methyl-2-(methylthio)propylcarbamoyl)-4-chloro-6-methylphenyl)-3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 16e. Bioassay results indicated that most of the synthesized compounds showed superior insecticidal activities against Mythimna separata and Plutella xylostella when compared with the positive control cyantraniliprole. In particular, N-(2-(2-methyl-2-(N-cyanomethylsulfideimino)propylcarbamoyl)-4-chloro-6-methylphenyl)-3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 17e showed excellent insecticidal activity against Mythimna separata, with a mortality rate of 100% at a concentration of 1μgmL-1. These results indicated that sulfide, N-cyanomethylsulfilimine, and N-cyanomethylsulfoximine moieties, as important active substructures, could improve or maintain the activity of the anthranilic diamide and promote novel pesticide development.

Reversible inactivation of bovine plasma amine oxidase by cysteamine and related analogs

Cysteamine (1) was reported many years ago to reversibly inhibit lentil seedling amine oxidase, through the formation of a complex with thioacetaldehyde, the turnover product of 1. Herein, cysteamine (1) and its analogs 2-(methylamino)ethanethiol (3) and 3-aminopropanethiol (6) were found to be reversible inhibitors of bovine plasma amine oxidase (BPAO), but 2-(methylthio)ethylamine (7) was determined to be a weak irreversible inhibitor of BPAO. Based on our results, indicating the necessity of a sulfhydryl-amine for reversible inactivation of BPAO, the failure of inhibited BPAO to recover activity after gel filtration, the first-order kinetics of activity recovery upon dialysis, and 2,4,6-trihydroxyphenylalanine quinine (TPQ) cofactor transformation which indicated from the results of phenylhydrazine titration and substrate protection, we propose a mechanism for the reversible inactivation of BPAO by 1 involving the formation of a cofactor adduct, thiazolidine, between BPAO and 1.

INDOLYLMETHYL-MORPHOLINE DERIVATIVES AS KINASE INHIBITORS

A series of morpholine derivatives, substituted in the 4-position by a substituted carbonyl or sulfonyl moiety, and in the 3-position by an optionally substituted indol-3-ylmethyl group, being selective inhibitors of PI3 kinase enzymes, are accordingly of