69504-98-9Relevant academic research and scientific papers
COMBINATION CLAISEN-NITRILE OXIDE ANNULATION. A STRATEGY FOR RING CONSTRUCTION WITH RIGID STEREOCONTROL DICTATED BY AN ALLYLIC HYDROXYL GROUP.
Curran, Dennis P.,Jacobs, Patricia B.
, p. 2031 - 2034 (2007/10/02)
A new method for annulation of rings onto existing allylic alcohol derivatives is presented.The sequence involves Claisen rearrangement followed by nitrile oxide-olefin cycloaddition.Control of relevant stereochemistry is emphasized.
