6951-70-8 Usage
Uses
Used in Pharmaceutical Industry:
Ethanone,1-(2-amino-4,5-dichlorophenyl)is used as a building block for the production of various medications. Its unique chemical structure allows it to be incorporated into a wide range of pharmaceutical compounds, making it a valuable asset in the development of new drugs.
Used in Agricultural Sector:
In the agricultural sector, Ethanone,1-(2-amino-4,5-dichlorophenyl)is used in the development of pesticides and herbicides. Its chemical properties make it effective in controlling pests and unwanted plant growth, contributing to increased crop yields and productivity.
Safety Precautions:
It is important to handle Ethanone,1-(2-amino-4,5-dichlorophenyl)with caution and adhere to proper safety protocols when working with it due to its potential hazards. Proper handling and storage can help minimize risks and ensure the safe use of this chemical compound in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 6951-70-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,5 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6951-70:
(6*6)+(5*9)+(4*5)+(3*1)+(2*7)+(1*0)=118
118 % 10 = 8
So 6951-70-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H7Cl2NO/c1-4(12)5-2-6(9)7(10)3-8(5)11/h2-3H,11H2,1H3
6951-70-8Relevant articles and documents
Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase
Nittoli, Thomas,Curran, Kevin,Insaf, Shabana,DiGrandi, Martin,Orlowski, Mark,Chopra, Rajiv,Agarwal, Atul,Howe, Anita Y. M.,Prashad, Amar,Floyd, M. Brawner,Johnson, Bernard,Sutherland, Alan,Wheless, Karen,Feld, Boris,O'Connell, John,Mansour, Tarek S.,Bloom, Jonathan
, p. 2108 - 2116 (2008/02/06)
A series of potent anthranilic acid-based inhibitors of the hepatitis C NS5B polymerase has been identified. The inhibitors bind to a site on NS5B between the thumb and palm regions adjacent to the active site as determined by X-ray crystallography of the enzyme-inhibitor complex. Guided by both molecular modeling and traditional SAR, the enzyme activity of the initial hit was improved by approximately 100-fold, yielding a series of potent and selective NS5B inhibitors with IC50 values as low as 10 nM. These compounds were also inhibitors of the HCV replicon in cultured HUH7 cells.
4(1H)-Oxocinnoline-3-carboxylic acid derivatives
-
, (2008/06/13)
Amide and ester derivatives of substituted-4(1H)-oxocinnoline-3-carboxylic acids have antibacterial activity and are useful for inhibiting the growth of disease causing bacteria.