695181-55-6Relevant articles and documents
Fused pyrimidine based inhibitors of phosphodiesterase 7 (PDE7): Synthesis and initial structure-activity relationships
Kempson, James,Pitts, William J.,Barbosa, Joseph,Guo, Junqing,Omotoso, Omonike,Watson, Andrew,Stebbins, Karen,Starling, Gary C.,Dodd, John H.,Barrish, Joel C.,Felix, Raymond,Fischer, Karl
, p. 1829 - 1833 (2005)
A series of fused pyrimidine based inhibitors of PDE7 have been derived from an earlier screening lead 1. The synthesis, structure-activity relationships (SAR) and selectivity against several other PDE family members are described.