69520-13-4

Upstream product

• 599-70-2 ethyl phenyl sulfone 
• 123-11-5 4-methoxy-benzaldehyde 
• 814-49-3 diethyl chlorophosphate 
• 126613-16-9 1-(benzenesulfonyl)-2-(p-methoxyphenyl)acetylene 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 85143-33-5 (2-(4-methoxyphenyl)ethynyl)(phenyl)sulfane 
• 84384-30-5 4-(4-methoxyphenyl)-2-methyl-3-butyn-2-ol 
• 2749-97-5 4-methoxylphenylallene 
• 873-55-2 sodium benzenesulfonate 
• 768-60-5 4-methoxyphenylacetylen 

Relevant academic research and scientific papers

Photoredox-Catalyzed Hydrosulfonylation of Arylallenes

(Het)Arylallenes undergo hydrosulfonylation under photoredox-catalyzed conditions. The reaction gives vinyl sulfones in a regio- and diastereoselective manner, employing sodium sulfinates as the sulfonyl source and eosin Y as the photocatalyst. Indol-1-yl, pyrrol-1-yl, phenyl, and naphtylallenes might be used. Aliphatic allenes are incompatible with the reaction conditions.

Three types of products by carbon nucleophiles toward methoxyphenylacetylenic sulfones

Methoxy-arylacetylenic sulfones were examined to react with various carbanion nucleophiles to result in the three types of products; thus, (i) nucleophiles (MeLi·LiBr, Vinyl MgBr, LiCH2CN) showed the α-addition, however, (ii) Li-CC-TMS afforded β-addition (conjugate addition) products. The (iii) displacement reaction through α-addition/ isomerization/trans-elimination was enhanced by the presence of ortho-methoxy group at high temperature. The heteroatom nucleophiles (nitrogen, oxygen or sulfur atom) in a protic solvent provided only conjugate addition products as reported.

Palladium-catalyzed coupling of vinyl tosylates with arylsulfinate salts

The first palladium-catalyzed coupling of vinyl tosylates with arylsulfinate salts is described. A variety of cyclic and acyclic vinyl tosylates were coupled with aryl sulfinate salts using 2.5 mol % Pd2(dba)3/5.0 mol % XantPhos to g

One-pot synthesis of α-methyl vinyl sulfones from ethyl phenyl sulfones

Various α-methyl vinyl sulfones were synthesized by Horner-Emmons olefination of aldehydes and sulfonyl phosphonate generated from 1,1- dilithiosulfone.