69552-26-7Relevant articles and documents
Structural development of benzhydrol-type 1′-Acetoxychavicol Acetate (ACA) analogs as human leukemia cell-growth inhibitors based on Quantitative Structure-Activity Relationship (QSAR) analysis
Misawa, Takashi,Aoyama, Hiroshi,Furuyama, Taniyuki,Dodo, Kosuke,Sagawa, Morihiko,Miyachi, Hiroyuki,Kizaki, Masahiro,Hashimoto, Yuichi
experimental part, p. 1490 - 1495 (2009/10/01)
Benzhydrol-type analogs of 1′-acetoxychavicol acetate (ACA) were developed as inhibitors of human leukemia HL-60 cell growth based on quantitative structure-activity relationship (QSAR) analysis. An analog containing an anthracenyl moiety (8) was a potent inhibitor with the IC 50 value of 0.12 μM.