69557-54-6Relevant articles and documents
Expedient synthesis of benzimidazoles using amides
Kattimani, Pramod P.,Kamble, Ravindra R.,Meti, Gangadhar Y.
, p. 29447 - 29455 (2015/04/14)
In the present report an efficient, rapid, facile and inexpensive route for the synthesis of benzimidazoles using 1,2-arylenediamines and N,N-dimethylformamide in acidic medium under thermal/microwave condition is developed. This reaction was further explored with the different amides to afford a library of 2-substituted benzimidazoles. The advantage of the present synthetic method includes shorter reaction time, easy work up and excellent yields without using catalysts.
