69558-14-1

Upstream product

• 4613-15-4 benzyl 4-O-benzyl-α-L-rhamnopyranoside 
• 74-88-4 methyl iodide 

Downstream Products

• 136848-18-5 2-(methoxycarbonylethyl)phenyl 4-O-benzyl-2-O-methyl-α-L-rhamnopyranoside 
• 136848-24-3 p-(2-methoxycarbonylethyl)phenyl 2-O-methyl-3-O-<3-O-(2,3,4-tri-O-methyl-β-L-fucopyranosyl)-α-L-rhamnopyranosyl>-α-L-rhamnopyranoside 
• 136848-20-9 p-(2-methoxycarbonylethyl)phenyl 4-O-benzyl-2-O-methyl-3-O-(2,4-di-O-benzyl-α-L-rhamnopyranosyl)-α-L-rhamnopyranoside 
• 136848-19-6 p-(2-methoxycarbonylethyl)phenyl 4-O-benzyl-2-O-methyl-3-O-(3-O-acetyl-2,4-di-O-benzyl-α-L-rhamnopyranosyl)-α-L-rhamnopyranoside 
• 136848-22-1 p-(2-methoxycarbonylethyl)phenyl 4-O-benzyl-2-O-methyl-3-O-<2,4-di-O-benzyl-3-O-(2,3,4-tri-O-methyl-α-L-fucopyranosyl)-α-L-rhamnopyranosyl>-α-L-rhamnopyranoside 
• 136848-23-2 p-(2-methoxycarbonylethyl)phenyl 4-O-benzyl-2-O-methyl-3-O-<2,4-di-O-benzyl-3-O-(2,3,4-tri-O-methyl-β-L-fucopyranosyl)-α-L-rhamnopyranosyl>-α-L-rhamnopyranoside 
• 136848-16-3 3-[4-((2S,3R,4R,5S,6S)-4-Acetoxy-5-benzyloxy-3-methoxy-6-methyl-tetrahydro-pyran-2-yloxy)-phenyl]-propionic acid methyl ester 
• 136848-17-4 3-[4-((2R,3R,4R,5S,6S)-4-Acetoxy-5-benzyloxy-3-methoxy-6-methyl-tetrahydro-pyran-2-yloxy)-phenyl]-propionic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of the trisaccharide-protein conjugate of the phenolic glycolipid of Mycobacterium tuberculosis for the serodiagnosis of tuberculosis.

The trisaccharide segment of the phenolic glycolipid (PGL) of Mycobacterium tuberculosis, 2-O-methyl-3-O-[3-O-(2,3,4-tri-O-methyl-alpha-L-fucopyranosyl)-alpha-L- rhamnopyranosyl]-alpha-L-rhamnopyranose, was synthesized in the form of the p-(2-methoxycarbonylethyl)phenyl glycoside by a stepwise condensation. 2,4-Di-O-benzyl-3-O-acetyl-alpha-L-rhamnopyranosyl chloride was coupled to p-(2-methoxycarbonylethyl)phenyl 4-O-benzyl-2-O-methyl-alpha-L-rhamnopyranoside in the presence of silver triflate, and 2,3,4-tri-O-methyl-alpha-L-rhamnopyranosyl chloride was then coupled to the deacetylated disaccharide by the same procedure. The trisaccharide was deblocked and coupled to BSA, giving the neoglycoconjugate TB-NT-P-BSA. TB-NT-P-BSA showed its possibility as a useful tool for the serodiagnosis of tuberculosis.