6957-91-1

Usage

Uses

Used in Biochemical Research:
4-aminobenzaldehyde thiosemicarbazone is used as a versatile ligand for [its ability to form complexes with various metal ions] in metal ion coordination chemistry.
Used in Pharmaceutical Applications:
4-aminobenzaldehyde thiosemicarbazone is used as a potential medicinal compound for [its antimicrobial and antitumor activities].
Used in Disease Treatment:
4-aminobenzaldehyde thiosemicarbazone is used as a potential treatment for [tuberculosis and malaria] due to its medicinal properties.
Used in Environmental and Industrial Applications:
4-aminobenzaldehyde thiosemicarbazone is used as a chelating agent for [the removal of toxic metal ions from wastewater].

Upstream product

• 556-18-3 4-aminobenzaldehyde 
• 4346-94-5 thiosemicarbazide hydrochloride 
• 79-19-6 thiosemicarbazide 
• 5470-48-4 para-nitrobenzaldehyde thiosemicarbazone 

Downstream Products

• 92085-14-8 (4-thiosemicarbazonomethyl-anilino)-methanesulfonic acid 
• 100057-79-2 methoxy-acetic acid-(4-thiosemicarbazonomethyl-anilide) 
• 104-06-3 N-(4-[2-(aminocarbonothionyl)hydrazono]methylphenyl)acetamide 
• 87896-45-5 propionic acid-(4-thiosemicarbazonomethyl-anilide) 
• 102943-72-6 4-(N'-methyl-thioureido)-benzaldehyde-thiosemicarbazone 
• 61519-14-0 4-(N'-allyl-thioureido)-benzaldehyde-thiosemicarbazone 
• 51659-90-6 2-amino-5-(4-aminophenyl)-1,3,4-thiadiazole 
• 1338084-12-0 C₁₃H₁₀N₆O₂S 
• 1338084-00-6 C₁₅H₁₄N₆O₂S 
• 1338083-78-5 C₁₃H₁₁N₇O₂S 
• 1338084-33-5 C₁₈H₁₉N₇O₃S 
• 103754-57-0 (5Z)-5-(4-aminobenzylidene)-1,3-thiazolidine-2,4-dione 

Relevant academic research and scientific papers

Aryl thiosemicarbazones for the treatment of trypanosomatidic infections

Basing on a library of thiadiazole derivatives showing anti-trypanosomatidic activity, we have considered the thiadiazoles opened forms and reaction intermediates, thiosemicarbazones, as compounds of interest for phenotypic screening against Trypanosoma b

2,5-Disubstituted-1,3,4-oxadiazoles/thiadiazole as surface recognition moiety: Design and synthesis of novel hydroxamic acid based histone deacetylase inhibitors

The enzymatic inhibition of histone deacetylase activity has come out as a novel and effectual means for the treatment of cancer. Two novel series of 2-[5-(4-substitutedphenyl)-[1,3,4]-oxadiazol/thiadiazol-2-ylamino] -pyrimidine-5-carboxylic acid (tetrahydro-pyran-2-yloxy)-amides were designed and synthesized as novel hydroxamic acid based histone deacetylase inhibitors. The antiproliferative activities of the compounds were investigated in vitro using histone deacetylase inhibitory assay and MTT assay. The synthesized compounds were also tested for antitumor activity against Ehrlich ascites carcinoma cells in Swiss albino mice. The efforts were also made to establish structure-activity relationships among synthesized compounds. The results of the present studying indicates 2,5-disubstituted 1,3,4-oxadiazole/thiadiazole as promising surface recognition moiety for development of newer hydroxamic acid based histone deacetylase inhibitor.