69573-42-8

Basic information

• Product Name: 5-azido-1-phenylpentan-1-one
• Synonyms: 5-azido-1-phenylpentan-1-one
• CAS NO: 69573-42-8
• Molecular Weight: 203.244
• Mol File: 69573-42-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 5-azido-1-phenylpentan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-azido-1-phenylpentan-1-one(69573-42-8)
• EPA Substance Registry System: 5-azido-1-phenylpentan-1-one(69573-42-8)

Safety Data

• Hazardous Substances Data: 69573-42-8(Hazardous Substances Data)

Upstream product

• 942-93-8 5-Chloro-1-phenyl-1-pentanone 
• 13466-32-5 acetophenone dimethylhydrazone 
• 67888-71-5 N-(1-phenylethylidene)cyclohexylamine 
• 10487-96-4 1-phenylcyclopentanol 
• 4509-91-5 5-bromo-1-phenyl-1-pentanone 
• 3240-29-7 1-Phenylpent-4-en-1-one 
• 700-88-9 cyclopentylbenzene 
• 4144-62-1 5-benzoylvaleric acid 
• 1444-65-1 (RS)-2-phenylcyclohexanone 

Downstream Products

• 227937-21-5 (Z)-(5-azido-1-phenylpent-1-enyloxy)(tert-butyldimethyl)silane 
• 10413-00-0 5-oxo-5-phenylpentanenitrile 
• 227937-23-7 (S)-(-)-5-azido-2-hydroxy-1-phenylpentan-1-one 
• 227937-24-8 (R)-(-)-5-azido-2-hydroxy-1-phenylpentan-1-one 
• 148701-46-6 cis-(3S)-hydroxy-(2S)-phenylpiperidine 
• 57050-07-4 2-phenyl-3,4,5,6-tetrahydropyridine 
• 3389-54-6 n-benzoylpyrrolidine 

Relevant articles and documents

Visible Light-Driven, Copper-Catalyzed Aerobic Oxidative Cleavage of Cycloalkanones

A visible light-driven, copper-catalyzed aerobic oxidative cleavage of cycloalkanones has been presented. A variety of cycloalkanones with varying ring sizes and various α-substituents reacted well to give the distal keto acids or dicarboxylic acids with moderate to good yields.

In-situ-generation of alkylsilyl peroxides from alkyl hydroperoxides and their subsequent copper-catalyzed functionalization with organosilicon compounds

Alkylsilyl peroxides were generated in situ from the corresponding alkyl hydroperoxides using organosilicon compounds of the type Me3SiX (X = CN, N3, and halogens) and an amine base. Subsequent in situ copper-catalyzed homolytic cleavage of the alkylsilyl peroxides afforded alkyl radicals, which were then trapped with X (X = CN, N3, and halogens) to furnish products with new carbon-carbon, carbon-nitrogen, or carbon-halogen bonds in good to high yields.

Anti-Markovnikov Hydroazidation of Alkenes by Visible-Light Photoredox Catalysis

The anti-Markovnikov hydroazidation of alkenes has been accomplished under visible-light irradiation by using [Ir(dF(CF3)ppy)2(dtbbpy)]PF6 as the photocatalyst and trimethylsilyl azide as the azidating agent. The reactions were greatly facilitated by water, the beneficial effect of which can be attributed to its participation in the reaction as the hydrogen donor, as indicated by deuterium isotope experiments. The reactions proceed under solvent free conditions in the presence of water. 4-Dimethylaminopyridine also exhibited a beneficial effect on the reactions. The present method enabled hydroazidation of several types of unactivated alkenes with good yields and high regioselectivity.