69592-28-5

Upstream product

• 286-20-4 cyclohexane-1,2-epoxide 
• 75-31-0 isopropylamine 
• 75-30-9 2-iodo-propane 
• 6850-38-0 2-aminocyclohexanol 
• 38898-70-3 cis-2-amino-cyclohexanol-⁽¹⁾ 
• 75-26-3 isopropyl bromide 
• 931-16-8 (+/-)-trans-2-aminocyclohexanol 

Relevant academic research and scientific papers

Aluminium triflate: an efficient recyclable Lewis acid catalyst for the aminolysis of epoxides

Epoxides are powerful starting materials for a range of useful materials and can be converted into, amongst others, amino alcohols. In this work, a range of epoxides was ring-opened using various alkyl- and arylamines under the action of aluminium triflat

Calcium trifluoroacetate as an efficient catalyst for ring-opening of epoxides by amines under solvent-free conditions

Ca(CF3CO2)2 efficiently catalyzed the selective ring-opening of epoxides by amines leading to the synthesis of β-aminoalcohols. The reaction works well with various aromatic and aliphatic amines under solvent-free conditions. Corresponding β-aminoalcohols were obtained in excellent yields with high regioselectivity. The catalyst was easily prepared by reaction of CaH 2 in trifluoroacetic acid.

NOVEL CARBOSTYRIL DERIVATIVES

Novel carbostyril derivatives having platelet aggregation inhibitory action, antiinflamatory action, antiulcer action, vasodilatory action and phosphodiesterase inhibitory action and are useful for preventing or curing thrombus, arteriosclerosis, hypertension, asthma and other like diseases, and also useful as an antiinflamatory or anti-ulcer agent, represented by the formula wherein R1 is hydrogen, C1-4 alkyl, C2-4 alkenyl, phenyl-C1-4 alkyl-; R2 is hydrogen, a halogen atom, hydroxy, phenyl-C1-4 alkoxy; R3 is hydrogen, hydroxy, C1-4 alkyl; R4 is C3-8 cycloalkyl, substituted or unsubstituted phenyl, C3-8 cycloalkyl-C1-4 alkyl, 2-(3,4-dimethoxyphenyl)-ethyl, R5 is hydrogen, C1-8 alkyl, C2-4 alkenyl, phenyl, C3-8 cycloalkyl, phenyl-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkyl, m is an integer of 1 - 3, l and n which may be same or different, and are respectively 0 or an integer of 1 - 7 and the sum of l and n is not exceeding 7, the carbon-carbon bond at 3- and 4-positions in the carbostyril skelton is either single or double bond