69657-28-9Relevant articles and documents
Chiral-Anion-Mediated Asymmetric Heck-Matsuda Reaction of Acyclic Alkenyl Alcohols
Zhang, Tao,Li, Wen-Ao,Shen, Hong-Cheng,Chen, Shu-Sen,Han, Zhi-Yong
supporting information, p. 1473 - 1477 (2021/03/08)
Acyclic internal alkenes are a class of challenging substrates in asymmetric Heck-type reactions due to difficulties related to both reactivity and selectivity control. Employing acyclic alkenyl alcohols, an asymmetric Heck-Matsuda reaction is developed through the strategy of chiral anion phase transfer. Various chiral ketones could be obtained in high levels of enantioselectivity. A catalytic amount of dimethyl sulfoxide (DMSO) as an additive is crucial for the reaction to suppress the palladium-hydride-mediated side reactions.
Rhenium-catalyzed α-alkylation of enol acetates with alcohols or ethers
Umeda, Rui,Takahashi, Yuuki,Yamamoto, Takaaki,Iseki, Hideki,Osaka, Issey,Nishiyama, Yutaka
supporting information, p. 92 - 101 (2018/11/01)
When benzylic and allylic alcohols were treated with enol acetate in the presence of a catalytic amount of a rhenium complex, ReBr(CO)5, the carbon-carbon bond formation of the alcohols and enol acetate smoothly proceeded to give the corresponding ketones and aldehyde in moderate to good yields. For the reaction of allylic alcohols, γ,δ-unsaturated carbonyl compounds were obtained in good yields. When ethers were used instead of alcohols as the alkylated agent, two alkyl moieties on the ethers were utilized on the reaction.
Palladium-catalyzed site-selective arylation of aliphatic ketones enabled by a transient ligand
Pan, Lei,Yang, Ke,Li, Guigen,Ge, Haibo
supporting information, p. 2759 - 2762 (2018/03/21)
Transition metal-catalyzed direct C-H bond functionalization enabled by transient ligands has become an attractive topic. Here we report a palladium-catalyzed site-selective arylation of β-C(sp3)-H bonds in aliphatic ketones with β-alanine as the transient ligand.
