696609-56-0

Upstream product

• 508212-17-7 O-methoxymethyl homovanillic acid 
• 306-08-1 Homovanillic acid 
• 21038-22-2 O-(4-methoxybenzyl)hydroxylamine 
• 350803-06-4 (3-methoxy-4-methoxymethoxy-phenyl)-acetic acid pentafluorophenyl ester 

Downstream Products

• 350803-10-0 N-(2-hydroxy-ethyl)-N-(4-methoxy-benzyloxy)-2-(3-methoxy-4-methoxymethoxy-phenyl)-acetamide 

Relevant academic research and scientific papers

Vanilloid and isovanilloid analogues as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases

As aminoacyl adenylate surrogates, a series of methionyl and isoleucyl phenolic analogues containing bioisosteric linkers mimicking ribose have been investigated. Inhibition of synthesized compounds to the aminoacylation reaction by the corresponding Escherichia coli methionyl-tRNA and isoleucyl-tRNA synthetases indicated that 18 was found to be a potent inhibitor of isoleucyl-tRNA synthetase. A molecular modeling study demonstrated that in 18, isovanillate and hydroxamate served as proper surrogates for adenine and ribose in isoleucyl adenylate, respectively.