69663-58-7Relevant academic research and scientific papers
Potent 4-aminopiperidine based antimalarial agents
Brinner, Kristin M.,Powles, Mary Ann,Schmatz, Dennis M.,Ellman, Jonathan A.
, p. 345 - 348 (2007/10/03)
This paper describes potent antimalarial compounds effective against a multi-drug-resistant strain of P. falciparum (Dd2) with minimized toxicity, acceptable log D values, and stability to hepatocytic metabolism. A series of compounds with potent activity
Use of the butaclamol template in a search for antipsychotic agents with lessened side effects
Kukla,Bloss,Brougham
, p. 401 - 406 (2007/10/09)
A number of molecular similarities between the antipsychotic agents butaclamol and clozapine were noted. Based on the premise that this was a strong indicator of a common mechanism of action (i.e., binding at the antagonist state of dopamine receptor), a
