696642-13-4

Upstream product

• 696641-84-6 C₃₃H₆₃IO₈ 
• 608532-23-6 2,2-Dimethyl-propionic acid 4-((2R,5S)-5-{(1S,4R)-1,4-bis-methoxymethoxy-4-[(2R,5R)-5-((R)-1-methoxymethoxy-undecyl)-tetrahydro-furan-2-yl]-butyl}-tetrahydro-furan-2-yl)-butyl ester 
• 608532-19-0 2,2-Dimethyl-propionic acid 4-((2R,5S)-5-{(1S,4R)-1-acetoxy-4-hydroxy-4-[(2R,5R)-5-((R)-1-methoxymethoxy-undecyl)-tetrahydro-furan-2-yl]-butyl}-tetrahydro-furan-2-yl)-butyl ester 
• 608532-21-4 2,2-Dimethyl-propionic acid 4-((2R,5S)-5-{(1S,4R)-1,4-dihydroxy-4-[(2R,5R)-5-((R)-1-methoxymethoxy-undecyl)-tetrahydro-furan-2-yl]-butyl}-tetrahydro-furan-2-yl)-butyl ester 
• 608532-16-7 2,2-Dimethyl-propionic acid 4-((2R,5S)-5-{(Z)-(1S,4R)-1-acetoxy-4-hydroxy-4-[(2R,5R)-5-((R)-1-methoxymethoxy-undecyl)-tetrahydro-furan-2-yl]-but-2-enyl}-tetrahydro-furan-2-yl)-butyl ester 
• 608532-24-7 4-((2R,5S)-5-{(1S,4R)-1,4-Bis-methoxymethoxy-4-[(2R,5R)-5-((R)-1-methoxymethoxy-undecyl)-tetrahydro-furan-2-yl]-butyl}-tetrahydro-furan-2-yl)-butan-1-ol 
• 608532-12-3 (R)-1-[(2R,5R)-5-((R)-1-Methoxymethoxy-undecyl)-tetrahydro-furan-2-yl]-prop-2-en-1-ol 
• 198541-55-8 (R)-4-(tert-Butyl-diphenyl-silanyloxy)-5-((S)-5-methyl-2-oxo-2,5-dihydro-furan-3-yl)-pentanal 

Downstream Products

• 129138-51-8 bullatanocin 
• 696642-28-1 (S)-3-[(R)-9-((2R,5S)-5-{(1S,4R)-1,4-Bis-methoxymethoxy-4-[(2R,5R)-5-((R)-1-methoxymethoxy-undecyl)-tetrahydro-furan-2-yl]-butyl}-tetrahydro-furan-2-yl)-2-(tert-butyl-diphenyl-silanyloxy)-nonyl]-5-methyl-5H-furan-2-one 

Relevant academic research and scientific papers

Total Synthesis of the Nonadjacently Linked Bis-tetrahydrofuran Acetogenin Bullatanocin (Squamostatin C)

The total synthesis of the nonadjacently linked bis-THF acetogenin bullatanocin (squamostatin C) is described. The synthetic strategy is a modular one based on three components, two mono-THF alkenes and a butenolide precursor, and the olefin cross-metathesis and Wittig olefination as the segment-coupling reactions. The synthesis confirms the structure of the natural product, and its convergent design makes it especially attractive for analogue synthesis.