696660-07-8Relevant academic research and scientific papers
Stereoselective isomerisation of N-Allyl aziridines into geometrically stable Z enamines by using rhodium hydride catalysis
Tsang, Derek S.,Yang, Sharon,Alphonse, France-Aimee,Yudin, Andrei K.
, p. 886 - 894 (2008/09/21)
In the presence of rhodium(I) hydride catalysts, tertiary N-allylamines are known to isomerise into E enamines. In contrast, we have recently found that N-allylaziridines isomerise to form Z enamines. On the basis of literature data, the most likely mecha
Unusual Selectivity of Unprotected Aziridines in Palladium-Catalyzed Allylic Amination Enables Facile Preparation of Branched Aziridines
Watson, Iain D. G.,Styler, Sarah A.,Yudin, Andrei K.
, p. 5086 - 5087 (2007/10/03)
Functionalized branched aziridines can be prepared in high yields and with high levels of regioselectivity using unprotected aziridines as nitrogen sources in palladium-catalyzed allylic amination. High levels of enantioselectivity can be achieved with BINAP on palladium. This methodology allows for strategic placement of an aziridine-containing fragment within a complex molecule environment for further elaboration. Copyright
