69668-92-4Relevant academic research and scientific papers
Studies on the Cu(I)-catalyzed regioselective anti-carbometallation of secondary terminal propargylic alcohols
Lu, Zhan,Ma, Shengming
, p. 2655 - 2660 (2007/10/03)
A highly regioselective Cu(I)-catalyzed anti-carbometallation of secondary terminal propargylic alcohols with 1° alkyl or aryl Grignard reagents affording 2-substituted allylic alcohols was developed. By using this method, optically active allylic alcohols can be prepared from the optically active propargylic alcohols without obvious loss of the enantiopurity. The cyclic organometallic intermediate formed may undergo an iodination or a Pd(0)-catalyzed coupling reaction to afford stereo-defined allylic alcohols.
Acetyl chloride-ethanol brings about a remarkably efficient conversion of allyl acetates into allyl chlorides
Yadav, Veejendra K.,Ganesh Babu
, p. 9111 - 9116 (2007/10/03)
AcCl-EtOH transforms primary and secondary allyl acetates into allyl chlorides that retain the olefinic bond in the more stable position. Whereas secondary allyl alcohols also react with almost the same efficacy as the acetates, the reactions of primary allyl alcohols that possess 1, 2-disubstituted alkenes are very slow. The products are isolated in high state of purity simply by removal of the volatiles.
Selective 1,4-reduction of α,β-unsaturated carbonyl compounds by combined use of bis(l,3-diketonato)cobait(II) complex and diisobutylaluminum hydride
Ikeno, Taketo,Kimura, Tomomi,Ohtsuka, Yuhki,Yamada, Tohru
, p. 96 - 98 (2007/10/03)
By the combined use of Co(acac)2 with DIBAL, various α,β-unsaturated carbonyl compounds such as enones, α,β-unsaturated carboxylates and carboxamides were selectively reduced in a 1,4-manner to obtain the corresponding 1,4-reduced products in good-to-high yields. Thieme.
