6970-19-0

Basic information

• Product Name: 3,4,5-TRIETHOXYBENZOIC ACID
• Synonyms: Benzoic acid, 3,4,5-triethoxy-;LABOTEST-BB LT00848146;AKOS BBS-00007827;3,4,5-TRIETHOXYBENZOIC ACID;3,4,5-Triethoxybenzoic acid, 98+%;3,4,5-Triethoxybenzoic acid,97%
• CAS NO: 6970-19-0
• Molecular Formula: C₁₃H₁₈O₅
• Molecular Weight: 254.28
• EINECS: 230-192-3
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 6970-19-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 109-112 °C
• Boiling Point: 357.49°C (rough estimate)
• Flash Point: 135.7 °C
• Appearance: Beige/Amorphous Powder
• Density: 1.2092 (rough estimate)
• Vapor Pressure: 3.34E-06mmHg at 25°C
• Refractive Index: 1.4825 (estimate)
• PKA: 4.29±0.10(Predicted)
• BRN: 2659063
• CAS DataBase Reference: 3,4,5-TRIETHOXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,5-TRIETHOXYBENZOIC ACID(6970-19-0)
• EPA Substance Registry System: 3,4,5-TRIETHOXYBENZOIC ACID(6970-19-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-37/39-26
• Hazardous Substances Data: 6970-19-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H18O5/c1-4-16-10-7-9(13(14)15)8-11(17-5-2)12(10)18-6-3/h7-8H,4-6H2,1-3H3,(H,14,15)/p-1

Upstream product

• 861320-32-3 3,5,7-triethoxy-2-(3,4,5-triethoxy-phenyl)-chromen-4-one 
• 149-91-7 3,4,5-trihydroxybenzoic acid 
• 99-24-1 methyl galloate 
• 39666-77-8 methyl 3,4,5-triethoxybenzoate 
• 64-67-5 diethyl sulfate 

Downstream Products

• 39666-77-8 methyl 3,4,5-triethoxybenzoate 
• 911701-67-2 2-bromo-3,4,5-triethoxybenzoic acid 
• 184963-78-8 3',4',5'-triethoxypropiophenone 
• 1623785-48-7 7-methoxy-2-(3,4,5-triethoxybenzyl)-6-(triisopropylsilyloxy)-1,2,3,4-tetrahydroisoquinoline 
• 1623785-60-3 7-methoxy-6-sulfamoyloxy-2-(3,4,5-triethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline 
• 1623785-54-5 6-hydroxy-7-methoxy-2-(3,4,5-triethoxybenzyl)-1,2,3,4-tetra-hydroisoquinoline 
• 1064205-97-5 6-hydroxy-2-(3,4,5-triethoxybenzoyl)-1,2,3,4-tetrahydroisoquinoline 
• 1064206-24-1 6-hydroxy-2-(3,4,5-triethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline 
• 1623785-43-2 7-methoxy-2-(3,4,5-triethoxybenzoyl)-6-(triisopropylsilyloxy)-1,2,3,4-tetrahydroisoquinoline 
• 1613027-19-2 4,5,6-tris(benzyloxy)-2-phenylisoindoline-1,3-dione 

Relevant articles and documents

DIARYL TREHALOSE COMPOUNDS AND USES THEREOF

Disclosed herein are diaryl trehalose compounds and methods of use thereof, for example as vaccine adjuvants.

Depigmenting activity and low cytotoxicity of alkoxy benzoates or alkoxy cinnamte in cultured melanocytes

To obtain effective and safe topical depigmenting agents, we synthesized hydroxybenzoates, alkoxybenzoates, and 3,4,5-trimethoxycinnamate containing a thymol moiety and screened then for high-level inhibitory activity against melanin synthesis in cultured melanocytes. Eight compounds were tested for their depigmenting effect and cytotoxicity using a murine melanocyte cell line. We found that 3,4,5-trialkoxybenzoates and 3,4,5-trimethoxycinnamate, synthesized by conjugating 3,4,5-trialkoxybenzoic acids and 3,4,5-trimethoxycinnmic acid with thymol, showed a potent depigmenting effect and low cytotoxicity. Compound 4h, 5-methyl-2-(methylethyl)phenyl (2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoate, showed the most potent depigmenting effect (IC50=10 μM) with low cytotoxicity (IC50=200 μM).

Ubiquinones and related compounds. XXII. Synthesis of 2,3-dimethoxy-5-methyl-1,4-benzoquinone and its ethylhomologues

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