6971-11-5Relevant academic research and scientific papers
Preparation method of modified silane coupling agent
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Paragraph 0026; 0027, (2016/10/31)
A preparation method of a modified silane coupling agent comprises: (1), dissolving mono-anhydride or tetracid dianhydride in glacial acetic acid, adding allylamine according to a molar ratio of the mono-anhydride or tetracid dianhydride to the allylamine being 1:1 or 1:2, stirring and reflowing for 3-24 h, adding water, filtering, washing, and drying to obtain an imide product; (2), dissolving the imide product in an aprotic solvent of medium polarity, adding 0.2 ml or 0.35 ml of a catalyst and trialkoxysilane according to a molar ratio to the imide product being 1:1 or 2:1, and reacting at 50-70 DEG C for 5-48 h, distilling at reduced pressure to remove a low-boiling-point fraction to obtain a product.Least catalyst is used at the premise of ensuring optimal catalytic efficiency so that lowest production cost is achieved.
RCM approach to complex polycyclic α-hydroxy γ-lactams: Synthesis of indolizinones and pyrroloazepinones
Gomez-Sanjuan, Asier,Sotomayor, Nuria,Lete, Esther
, p. 6722 - 6732 (2013/11/06)
The allylmagnesium chloride addition/RCM sequence on N-alkenyl-substituted imides provides a mild access to indolizinone and pyrroloazepinone derivatives with the α-hydroxy-γ-lactam framework. The procedure can be applied to the asymmetric synthesis of this type of derivatives, by employing a 2-exo-hydroxy-10-bornylsulfinyl group as a chiral auxiliary. Further functionality can be introduced at the angular position through an α-amidoalkylation reaction. The sequence of allylmagnesium chloride addition/RCM sequence using N-alkenyl-substituted imides provides mild access to indolizinone and pyrrolozepinone derivatives with an α-hydroxy-γ- lactam framework. Copyright
